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公开(公告)号：EP2350304B1
公开(公告)日：2016-12-14
申请号：EP09824182.1
申请日：2009-10-30
发明人： CUNNINGHAM, Mark , SAN MATEO, Lani , SARISKY, Robert, T. , SWEET, Raymond , RAUCHENBERGER, Robert , RUTZ, Mark , FENG, Yiqing , HEERINGA, Katharine , LUO, Jinquan , TENG, Fang , TEPLYAKOV, Alexey , WU, Sheng-jiun
IPC分类号： C12P21/06 , C07K16/28 , A61K39/395
CPC分类号： C07K16/2896 , A61K39/39533 , A61K39/3955 , A61K2039/505 , C07H21/04 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N5/10 , C12N5/12 , C12N15/117 , C12N15/63 , C12N2310/17 , A61K39/00 , A61K2300/00
摘要： Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
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公开(公告)号：EP3331563A1
公开(公告)日：2018-06-13
申请号：EP16833880.4
申请日：2016-08-04
发明人： FRANSSON, Johan , LEU, Jocelyn , OBMOLOVA, Galina , SURI, Anish , TENG, Fang , TEPLYAKOV, Alexey , ZHOU, Hong
IPC分类号： A61K39/395 , C07K16/28
CPC分类号： C07K16/2875 , A61K45/06 , C07K2317/21 , C07K2317/24 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/71 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： The present invention relates to antagonistic antibodies specifically binding CD154, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号：EP2425008A1
公开(公告)日：2012-03-07
申请号：EP10770329.0
申请日：2010-04-29
发明人： CUNNINGHAM, Mark , FENG, Yiqing , HEERINGA, Katharine , LUO, Jinquan , RAUCHENBERGER, Robert , RUTZ, Mark , SAN MATEO, Lani , SARISKY, Robert , SWEET, Raymond , TENG, Fang , TEPLYAKOV, Alexey , WU, Sheng-jiun
IPC分类号： C12P21/06
CPC分类号： C07K16/2896 , A61K2039/505 , C07K2299/00 , C07K2317/21 , C07K2317/24 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/73 , C07K2317/76 , C07K2317/94 , C07K2319/00
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公开(公告)号：EP3020822A1
公开(公告)日：2016-05-18
申请号：EP15185339.7
申请日：2010-04-29
发明人： CUNNINGHAM, Mark , FENG, Yiqing , HEERINGA, Katharine , LUO, Jinquan , RAUCHENBERGER, Robert , RUTZ, Mark , SAN MATEO, Lani , SARISKY, Robert T. , SWEET, Raymond , TENG, Fang , TEPLYAKOV, Alexey , WU, Sheng-jiun
IPC分类号： C12P21/06 , C07K16/28 , A61K39/395
CPC分类号： C07K16/2896 , A61K2039/505 , C07K2299/00 , C07K2317/21 , C07K2317/24 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/73 , C07K2317/76 , C07K2317/94 , C07K2319/00
摘要： Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
摘要翻译： 公开了Toll样受体3（TLR3）抗体拮抗剂，编码TLR3抗体拮抗剂或其片段的多核苷酸，以及制备和使用前述物质的方法。
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公开(公告)号：EP2425008B1
公开(公告)日：2015-09-16
申请号：EP10770329.0
申请日：2010-04-29
发明人： CUNNINGHAM, Mark , FENG, Yiqing , HEERINGA, Katharine , LUO, Jinquan , RAUCHENBERGER, Robert , RUTZ, Mark , SAN MATEO, Lani , SARISKY, Robert T. , SWEET, Raymond , TENG, Fang , TEPLYAKOV, Alexey , WU, Sheng-jiun
IPC分类号： C12P21/06 , C07K16/28 , A61K39/395
CPC分类号： C07K16/2896 , A61K2039/505 , C07K2299/00 , C07K2317/21 , C07K2317/24 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/73 , C07K2317/76 , C07K2317/94 , C07K2319/00
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6.发明公开TOLL-LIKE RECEPTOR 3 ANTAGONISTS FOR THE TREATMENT OF METABOLIC AND CARDIOVASCULAR DISEASES 审中-公开Toll样受体3拮抗剂进行新陈代谢和心血管疾病的治疗
公开(公告)号：EP2755685A1
公开(公告)日：2014-07-23
申请号：EP11872271.9
申请日：2011-09-12
发明人： CUNNINGHAM, Mark , FENG, Yiqing , HEERINGA, Katharine , LUO, Jinquan , RAUCHENBERGER, Robert , RUTZ, Mark , SAN MATEO, Lani , SARISKY, Robert , STOJANOVIC-SUSULIC, Vedrana , SWEET, Raymond , TENG, Fang , TEPLYAKOV, Alexey , WU, Linda , WU, Sheng-Jiun
IPC分类号： A61K39/395
CPC分类号： C07K16/2896 , A61K2039/505 , A61K2039/545 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
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7.发明公开TOLL-LIKE RECEPTOR 3 ANTAGONISTS FOR THE TREATMENT OF METABOLIC AND CARDIOVASCULAR DISEASES 审中-公开TOLL样受体3拮抗剂治疗代谢性心血管疾病和心血管疾病
公开(公告)号：EP2900266A1
公开(公告)日：2015-08-05
申请号：EP13841754.8
申请日：2013-09-20
发明人： CUNNINGHAM, Mark , FENG, Yiqing , HEERINGA, Katharine , LUO, Jinquan , RAUCHENBERGER, Robert , RUTZ, Mark , SAN MATEO, Lani , SARISKY, Robert , STOJANOVIC-SUSULIC, Vedrana , SWEET, Raymond , TENG, Fang , TEPLYAKOV, Alexey , WU, Linda , WU, Sheng-Jiun , LACY, Eilyn
IPC分类号： A61K39/395 , C07K16/00
CPC分类号： C07K16/2896 , A61K2039/505 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
摘要翻译： Toll样受体3（TLR3）抗体拮抗剂，公开了编码TLR3抗体拮抗剂或其片段的多核苷酸，以及制备和使用前述的方法。
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