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公开(公告)号：EP3597219A1
公开(公告)日：2020-01-22
申请号：EP19192657.5
申请日：2013-04-29
发明人： DUFFY, Karen , HEALY, Catherine , LAMB, Roberta , MALAVIYA, Ravi , PRATTA, Michael , FURSOV, Natalie , LUO, Jinquan , NASO, Michael , TORNETTA, Mark , WHEELER, John , WU, Sheng-Jiun , HALL, LeRoy
摘要： The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.
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公开(公告)号：EP2552961A1
公开(公告)日：2013-02-06
申请号：EP11763357.8
申请日：2011-03-30
发明人： ALMAGRO, Juan, Carlos , BRANIGAN, Patrick , KANE, Colleen , STROHL, William , TAUDTE, Susann , TORNETTA, Mark , WHEELER, John
IPC分类号： C07K16/24 , A61K39/395
CPC分类号： C07K16/244 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to target binding members (e.g., antibodies) that bind a specified epitope of human IL-25. The invention also relates to target binding members (e.g., antibodies) that comprise one or more humanized antibody VL domain sequences and bind IL-25. The invention further relates to compositions comprising target binding members (e.g., antibodies) that bind IL-25, methods of producing such target binding members, and uses of such target binding members for the treatment or prevention of diseases and conditions (e.g., asthma, inflammatory bowel disease).
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公开(公告)号：EP2844292B1
公开(公告)日：2019-08-21
申请号：EP13785158.0
申请日：2013-04-29
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4.发明授权DESIGN AND GENERATION OF HUMAN DE NOVO PIX PHAGE DISPLAY LIBRARIES VIA FUSION TO PIX OR PVII, VECTORS, ANTIBODIES AND METHODS 有权规划和人力从头PIX噬菌体展示库由Fusion的创建到PIX OR的pVII，向量，抗体和方法
公开(公告)号：EP2231904B1
公开(公告)日：2016-01-13
申请号：EP08867683.8
申请日：2008-11-21
发明人： TSUI, Ping , SHI, Lei , LU, Jin , WHEELER, John , WHITAKER, Brian , BOROZDINA-BIRCH, Lionella , ALMAGRO, Juan , AMEGADZIE, Bernard , TORNETTA, Mark , REDDY, Ramachandra , KNIGHT, David , LUO, Jinquan , SWEET, Raymond
IPC分类号： C40B40/02
CPC分类号： C12N15/1037 , C40B30/04 , C40B40/02
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公开(公告)号：EP2552961B1
公开(公告)日：2017-12-20
申请号：EP11763357.8
申请日：2011-03-30
发明人： ALMAGRO, Juan, Carlos , BRANIGAN, Patrick , KANE, Colleen , STROHL, William , TAUDTE, Susann , TORNETTA, Mark , WHEELER, John
IPC分类号： C07K16/24 , A61K39/395
CPC分类号： C07K16/244 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to target binding members (e.g., antibodies) that bind a specified epitope of human IL-25. The invention also relates to target binding members (e.g., antibodies) that comprise one or more humanized antibody VL domain sequences and bind IL-25. The invention further relates to compositions comprising target binding members (e.g., antibodies) that bind IL-25, methods of producing such target binding members, and uses of such target binding members for the treatment or prevention of diseases and conditions (e.g., asthma, inflammatory bowel disease).
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公开(公告)号：EP2844292A2
公开(公告)日：2015-03-11
申请号：EP13785158.0
申请日：2013-04-29
发明人： DUFFY, Karen , HEALY, Catherine , LAMB, Roberta , MALAVIYA, Ravi , PRATTA, Michael , FURSOV, Natalie , LUO, Jinquan , NASO, Michael , TORNETTA, Mark , WHEELER, John , WU, Sheng-Jiun , HALL, LeRoy
IPC分类号： A61K39/395 , C07K16/24
CPC分类号： C07K16/2866 , A61K38/012 , A61K39/3955 , A61K2039/505 , C07K16/44 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.
摘要翻译： 本发明涉及ST2L拮抗剂，编码拮抗剂或其片段的多核苷酸，以及制备和使用上述物质的方法。
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