专利检索 ap:("Janssen Pharmaceutica NV") AND inv:"QUEROLLE, Olivier, Alexis, Georges" 第 1 页

1.

发明授权
TRICYCLIC HETEROCYCLES FOR THE TREATMENT OF CANCER 有权

公开(公告)号：EP3353177B1

公开(公告)日：2020-06-03

申请号：EP16770011.1

申请日：2016-09-22

申请人： Janssen Pharmaceutica NV

发明人： ANGIBAUD, Patrick, René , BROGGINI, Diego, Fernando, Domenico , COLOMBEL, Hélène, France, Solange , CUYCKENS, Filip, Albert, C , HOSTYN, Steven, Anna , JONES, Russell, Mark , QUEROLLE, Olivier, Alexis, Georges , VERMEULEN, Wim

IPC分类号： C07D471/04 , C07D487/04 , A61K31/519 , A61P35/00

2.

发明公开
SPIRO BICYCLIC INHIBITORS OF MENIN-MLL INTERACTION 审中-公开

公开(公告)号：EP3512857A1

公开(公告)日：2019-07-24

申请号：EP17768428.9

申请日：2017-09-13

申请人： Janssen Pharmaceutica NV

发明人： ANGIBAUD, Patrick, René , PANDE, Vineet , HERKERT, Barbara , KROSKY, Daniel, Jason , QUEROLLE, Olivier, Alexis, Georges , PILATTE, Isabelle, Noëlle, Constance , PATRICK, Aaron, Nathaniel

IPC分类号： C07D519/00 , A61K45/06 , A61P35/00

3.

发明公开
PYRIDAZINES OR 1,2,4-TRIAZINES SUBSTITUTED BY SPIROCYCLIC AMINES 审中-实审

公开(公告)号：EP4347600A1

公开(公告)日：2024-04-10

申请号：EP22729426.1

申请日：2022-06-02

申请人： JANSSEN Pharmaceutica NV

发明人： CAI, Wei , DAI, Xuedong , QUEROLLE, Olivier, Alexis, Georges , THURING, Johannes, Wilhelmus, J. , DENG, Xiangjun , FANG, Lichao , FU, Liqiang , LI, Ming , LIU, Lianzhu , LIU, Yingtao , XU, Yanping , PANDE, Vineet

IPC分类号： C07D487/10 , A61P3/10 , A61P35/00 , A61K31/53

4.

发明授权
HETEROAROMATIC DERIVATIVES AS NIK INHIBITORS 有权

公开(公告)号：EP3478675B1

公开(公告)日：2020-04-22

申请号：EP17739902.9

申请日：2017-06-29

申请人： Janssen Pharmaceutica NV

发明人： STANSFIELD, Ian , QUEROLLE, Olivier, Alexis, Georges , LIGNY, Yannick, Aimé, Eddy , GROSS, Gerhard, Max , JACOBY, Edgar , MEERPOEL, Lieven , GREEN, Simon, Richard , HYND, George , KULAGOWSKI, Janusz, Jozef , MACLEOD, Calum , MANN, Samuel, Edward

IPC分类号： C07D405/14 , C07D413/14 , C07D403/14 , C07D405/12 , C07D417/14 , A61K31/505 , A61P35/00 , A61P37/00

5.

发明公开
FUSED BICYCLIC INHIBITORS OF MENIN-MLL INTERACTION 审中-公开

公开(公告)号：EP3512858A1

公开(公告)日：2019-07-24

申请号：EP17768750.6

申请日：2017-09-13

申请人： Janssen Pharmaceutica NV

发明人： ANGIBAUD, Patrick, René , PANDE, Vineet , HERKERT, Barbara , KROSKY, Daniel, Jason , QUEROLLE, Olivier, Alexis, Georges , PATRICK, Aaron Nathaniel

IPC分类号： C07D519/04 , A61P35/00 , A61P3/10

6.

发明公开
QUINOXALINE AND PYRIDOPYRAZINE DERIVATIVES AS PI3KBETA INHIBITORS 审中-公开

公开(公告)号：EP3359533A1

公开(公告)日：2018-08-15

申请号：EP16778024.6

申请日：2016-10-07

申请人： Janssen Pharmaceutica NV

发明人： ANGIBAUD, Patrick, René , QUEROLLE, Olivier, Alexis, Georges , BERTHELOT, Didier, Jean-Claude , MEYER, Christophe , WILLOT, Matthieu, Philippe, Victor , MEERPOEL, Lieven , JOUSSEAUME, Thierry, François, Alain, Jean

IPC分类号： C07D403/12 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/06 , C07D403/14 , C07D413/04 , C07D413/06 , C07D241/14 , C07D417/06 , C07D471/04 , C07D487/02 , C07D491/10 , C07D498/10 , C07D513/10 , A61K31/397 , A61K31/4025 , A61K31/498 , A61K31/4985

CPC分类号： C07D403/12 , C07D241/14 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/06 , C07D403/14 , C07D413/04 , C07D413/06 , C07D417/04 , C07D487/02 , C07D491/10 , C07D498/10 , C07D513/10

摘要： The present invention relates to substituted quinoxaline and pyridopyrazine derivatives of Formula (I) wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as pI3Kβ inhibitors. The invention further relates to pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.

7.

发明公开
HETEROCYCLYL LINKED IMIDAZOPYRIDAZINE DERIVATIVES AS PI3KBETA INHIBITORS 审中-公开
标题翻译：杂环酰基连接的咪唑并哒嗪衍生物作为PI3KBETA抑制剂

公开(公告)号：EP3233839A1

公开(公告)日：2017-10-25

申请号：EP15816165.3

申请日：2015-12-18

申请人： Janssen Pharmaceutica NV

发明人： MEVELLEC, Laurence, Anne , MEERPOEL, Lieven , COUPA, Sophie , PONCELET, Virginie, Sophie , PILATTE, Isabelle, Noëlle, Constance , PASQUIER, Elisabeth, Thérèse, Jeanne , BERTHELOT, Didier, Jean-Claude , QUEROLLE, Olivier, Alexis, Georges , MEYER, Christophe , ANGIBAUD, Patrick, René , DEMESTRE, Christophe, Gabriel, Marcel , MERCEY, Guillaume, Jean, Maurice

IPC分类号： C07D405/10 , A61K31/5355 , A61K31/541 , C07D487/04

CPC分类号： C07D487/04 , A61K31/5377 , C07B59/002 , C07B2200/05 , C07D405/10 , C07D519/00

摘要： wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as PI3Kβ inhibitors. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.

摘要翻译： 本发明涉及式（I）的杂环基连接的咪唑并哒嗪衍生物，其中各变量具有权利要求书中定义的含义。根据本发明的化合物可用作PI3Kβ抑制剂。本发明进一步涉及制备这种新化合物的方法，包含所述化合物作为活性成分的药物组合物以及所述化合物作为药物的用途。