公开(公告)号：EP2515877A2

公开(公告)日：2012-10-31

申请号：EP10803585.8

申请日：2010-12-20

申请人： Janssen R&D Ireland

发明人： SCHACHTER, Deborah M. ,  BAERT, Lieven Elvire Colette ,  KRAUS, Guenter ,  ZHANG, Qiang ,  CHUN, Iksoo

IPC分类号： A61K9/16 ,  A61K9/00

CPC分类号： A61L31/148 ,  A61K9/0024 ,  A61K9/0092 ,  A61K9/06 ,  A61K9/14 ,  A61K9/5031 ,  A61K9/5084 ,  A61K31/34 ,  A61K31/343 ,  A61K31/505 ,  A61K45/06 ,  A61L31/146 ,  A61K2300/00

摘要： A degradable, removable, pharmaceutical implant for the sustained release of one or more drugs in a subject, wherein the pharmaceutical implant is composed of a tube comprising an outer wall made of a degradable polymer completely surrounding a cavity, wherein the outer wall has a plurality of openings and wherein the cavity contains one or more sets of micro-particles, which micro-particles contain an active agent or a combination of two or more active agents, and wherein the size of the microparticles is selected such that the majority of the microparticles cannot pass through the openings.