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公开(公告)号：EP3919494A1
公开(公告)日：2021-12-08
申请号：EP20749430.3
申请日：2020-01-19
发明人： WU, Yong , GONG, Yanchun , ZHOU, Wenbin , QIN, Daan , ZHANG, Ya , LIU, Yongqiang
IPC分类号： C07D471/04 , C07D487/04 , C07D519/00 , A61K31/496 , A61K31/437 , A61P35/00 , A61P37/06 , A61P37/02 , A61P29/00
摘要： A 7-azaindole derivative having the structure of formula (I), a pharmaceutical composition containing the compound of formula (I), and uses of the compound in preparing a medicament for preventing or treating Janus kinase (JAK) family-related diseases, specifically, uses in preventing or treating inflammatory diseases related to protein tyrosine kinase.
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2.发明公开
公开(公告)号：EP3782621A1
公开(公告)日：2021-02-24
申请号：EP18915676.3
申请日：2018-04-16
发明人： ZHAO, Yanlei , ZHANG, Jianjun , LIU, Xuefang , GAO, Yuan , SUN, Hongbin , GONG, Yanchun , LIU, Yongqiang
摘要： The present invention relates to the technical field of medicine and relates to an instant release pharmaceutical preparation of an anticoagulant and a preparation method therefor. The instant release pharmaceutical preparation of an anticoagulant comprises a vicagrel compound or a pharmaceutically acceptable form thereof, the preparation is a tablet or a capsule, the vicagrel or the pharmaceutically acceptable form thereof is pro-vided at a suitable particle size, and the D90 thereof max ) of drug absorption. Further provided by the present invention is a method for preparing an instant release pharmaceutical preparation of an anticoagulant; according to the formulation of the drug-containing particles as disclosed by the present invention, a capsule or tablet instant release preparation having excellent stability may be obtained by means of a combination of optional preparation steps.
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公开(公告)号：EP3772516A1
公开(公告)日：2021-02-10
申请号：EP19815480.9
申请日：2019-06-06
发明人： WU, Yong , ZHOU, Wenbin , GONG, Yanchun , YUE, Yaoxiang , DENG, Jie , LIU, Yongqiang
IPC分类号： C07D471/22 , C07D471/04 , C07D487/22 , A61K31/519 , A61K31/5383 , A61P35/00 , A61P29/00
摘要： Disclosed in the present invention are a pyrazolo [1,5-a]pyrimidine derivative having a structure of formula (I), a pharmaceutical composition comprising the compound of formula (I), and use of the compound in the preparation of a medicament for preventing or treating diseases associated with tropomyosin receptor kinases, in particular for preventing or treating cancers associated with tropomyosin receptor kinases. Each substituent in formula (I) has the same definition as that in the description.
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