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1.发明公开NITRONE COMPOUNDS, PROCESS OF PREPARATION THEREOF, AND USE THEREOF IN MEDICAMENT MANUFACTURE 有权含氮化合物的方法，FOR THEIR和它们在药品生产
公开(公告)号：EP2265591A1
公开(公告)日：2010-12-29
申请号：EP09735184.5
申请日：2009-04-16
申请人： Jinan University
发明人： WANG, Yuqiang , JIANG, Jie , YU, Pei , SUN, Yewei , WANG, Linda , ZHANG, Zaijun
IPC分类号： C07D241/10 , C07D241/12 , C07D241/14 , C07D241/00 , C07D213/02 , C07D213/06 , C07D265/28 , C07D265/30 , C07D265/32 , C07D279/10 , C07D279/12 , C07D327/06 , C07D319/10 , C07D319/12 , C07D309/00 , C07D335/02 , A61K31/4965 , A61K31/435 , A61K31/436 , A61K31/437
CPC分类号： C07D241/12
摘要： The present invention provides novel nitrones, their preparation and use. The novel compounds have the following formula: I The compounds of the present invention have strong antioxidative activity, and are thrombolytic. These compounds can be used to treat and/or prevent diseases caused by overproduction of free radicals and/or formation of thrombus.
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2.发明授权NITRONE COMPOUNDS, PROCESS OF PREPARATION THEREOF, AND USE THEREOF IN MEDICAMENT MANUFACTURE 有权含氮化合物的方法，FOR THEIR和它们在药品生产
公开(公告)号：EP2265591B1
公开(公告)日：2013-07-03
申请号：EP09735184.5
申请日：2009-04-16
申请人： Jinan University
发明人： WANG, Yuqiang , JIANG, Jie , YU, Pei , SUN, Yewei , WANG, Linda , ZHANG, Zaijun
IPC分类号： C07D241/12 , A61K31/4965 , A61P25/00 , A61P9/00 , A61P29/00 , A61P27/02 , A61P35/00
CPC分类号： C07D241/12
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