专利检索 ap:("Juno Therapeutics, Inc." OR "Fred Hutchinson Cancer Research Center") AND inv:"TURTLE, Cameron, J." 第 1 页

1.

发明公开
METHODS FOR THE TREATMENT OF B CELL MALIGNANCIES USING ADOPTIVE CELL THERAPY 审中-公开

公开(公告)号：EP3463437A2

公开(公告)日：2019-04-10

申请号：EP17733663.3

申请日：2017-06-06

申请人： Juno Therapeutics, Inc. , Fred Hutchinson Cancer Research Center

发明人： TURTLE, Cameron, J. , MALONEY, David , RIDDELL, Stanley R. , GILBERT, Mark

IPC分类号： A61K39/00 , A61K35/17

2.

发明公开
BIOMARKERS AND USES THEREOF FOR SELECTING IMMUNOTHERAPY INTERVENTION 审中-公开

公开(公告)号：EP3580568A1

公开(公告)日：2019-12-18

申请号：EP18707487.7

申请日：2018-02-09

申请人： Fred Hutchinson Cancer Research Center , The University of Washington , Bloodworks Northwest

发明人： LILES, W., Conrad , TURTLE, Cameron, J. , MALONEY, David, G. , RIDDELL, Stanley, R. , WURFEL, Mark, M. , LOPEZ, Jose , CHUNG, Dominic , CHEN, Junmei

IPC分类号： G01N33/574

3.

发明授权
IDENTIFICATION OF CD8+ T CELLS THAT ARE CD161HI AND/OR IL18R(ALPHA)HI AND HAVE RAPID DRUG EFFLUX CAPACITY 有权
标题翻译：识别CD161HI和/或IL18R（ALPHA）HI并且具有快速药物递送能力的CD8 + T细胞

公开(公告)号：EP2245142B1

公开(公告)日：2018-03-07

申请号：EP09705748.3

申请日：2009-01-28

申请人： Fred Hutchinson Cancer Research Center

发明人： TURTLE, Cameron, J. , RIDDELL, Stanley, R.

IPC分类号： C12N5/0783 , A61K48/00 , G01N33/50

CPC分类号： A61K39/00 , A61K35/17 , A61K2039/515 , A61K2039/57 , A61K2039/572 , C12N5/0636 , C12N5/0638 , C12N2501/599 , G01N33/505 , G01N2333/54 , G01N2333/70557

摘要： This invention provides, among other things, methods for the identification and isolation of viable putative long-lived antigen-specific memory CD8 + T cell subsets (CMhi and EMhi) with high surface expression of CD161 and/or IL-18Ra and the capacity to rapidly efflux the fluorescent dye Rh123.

4.

发明公开
IDENTIFICATION OF CD8+ T CELLS THAT ARE CD161HI AND/OR IL18R(ALPHA)HI AND HAVE RAPID DRUG EFFLUX CAPACITY 有权
标题翻译：识别CD161HI和/或IL18R（ALPHA）HI并且具有快速药物递送能力的CD8 + T细胞

公开(公告)号：EP2245142A2

公开(公告)日：2010-11-03

申请号：EP09705748.3

申请日：2009-01-28

申请人： Fred Hutchinson Cancer Research Center

发明人： TURTLE, Cameron, J. , RIDDELL, Stanley, R.

IPC分类号： C12N5/08 , A61K48/00 , G01N33/53

CPC分类号： A61K39/00 , A61K35/17 , A61K2039/515 , A61K2039/57 , A61K2039/572 , C12N5/0636 , C12N5/0638 , C12N2501/599 , G01N33/505 , G01N2333/54 , G01N2333/70557

摘要： This invention provides, among other things, methods for the identification and isolation of viable putative long-lived antigen-specific memory CD8+ T cell subsets (CMhi and EMhi) with high surface expression of CD161 and/or IL-18Rα and the capacity to rapidly efflux the fluorescent dye Rh123.

摘要翻译： 本发明尤其提供了鉴定和分离具有高表面表达CD161和/或IL-18Rα的存活的长寿命抗原特异性记忆CD8 + T细胞亚群（CMhi和EMhi）的方法，以及快速流出荧光染料Rh123。

5.

发明公开
IDENTIFICATION OF CD8+ T CELLS THAT ARE CD161HI AND/OR IL18RALPHAHI AND HAVE RAPID DRUG EFFLUX CAPACITY 审中-公开

公开(公告)号：EP3363893A1

公开(公告)日：2018-08-22

申请号：EP17209395.7

申请日：2009-01-28

申请人： Fred Hutchinson Cancer Research Center

发明人： TURTLE, Cameron, J. , RIDDELL, Stanley, R.

IPC分类号： C12N5/0783 , A61K48/00 , G01N33/50 , A61K35/26 , A61K35/17 , A61K39/00

CPC分类号： A61K39/00 , A61K35/17 , A61K2039/515 , A61K2039/57 , A61K2039/572 , C12N5/0636 , C12N5/0638 , C12N2501/599 , G01N33/505 , G01N2333/54 , G01N2333/70557

摘要： This invention provides, among other things, methods for the identification and isolation of viable putative long-lived antigen-specific memory CD8 + T cell subsets (CMhi and EMhi) with high surface expression of CD161 and/or IL-18Ra and the capacity to rapidly efflux the fluorescent dye Rh123.

6.

发明公开
METHOD FOR ENHANCING CELLULAR IMMUNOTHERAPY 审中-公开

公开(公告)号：EP3946426A1

公开(公告)日：2022-02-09

申请号：EP20782166.1

申请日：2020-04-04

申请人： Nektar Therapeutics , Fred Hutchinson Cancer Research Center

发明人： MARCONDES, Antonio, Mario Querido , KIRK, Peter, Benedict , MIYAZAKI, Takahiro , TURTLE, Cameron, J. , RIDDELL, Stanley, R. , CHOU, Cassie, K. , FRÄSSLE, Simon, P.

IPC分类号： A61K38/20