公开(公告)号：EP1393746A1

公开(公告)日：2004-03-03

申请号：EP02717170.1

申请日：2002-04-16

申请人： Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute ,  KIRIN BEER KABUSHIKI KAISHA

发明人： MAEDA, Hiroaki ,  UMEHASHI, Misako ,  NOZAKI, Chikateru

IPC分类号： A61K39/395 ,  A61P31/04 ,  A61P31/12 ,  C07K16/12 ,  C07K16/08

CPC分类号： C07K16/1214 ,  A01K2217/05 ,  A61K2039/505 ,  C07K16/06 ,  C07K16/088 ,  C07K16/1081 ,  C07K16/1232 ,  C07K16/1271 ,  C07K16/1275 ,  Y02A50/39

摘要： A human polyclonal antibody having an antibacterial and/or antiviral activity with a desired titer and a wide spectrum; and human polyclonal antibody composition for preventing and treating infections which contain this antibody. The human polyclonal antibody composition for preventing or treating infections contain the human polyclonal antibody which is obtained by administering as immunogen a bacterium and/or a virus or a component of the bacterium and/or the virus to a non-human animal having a human antibody gene locus and has an antibody titer against the bacterium and/or the virus exceeding that of human pool plasma.

摘要翻译： 具有所需效价和广谱的抗细菌和/或抗病毒活性的人多克隆抗体; 和用于预防和治疗含有该抗体的感染的人多克隆抗体组合物。 用于预防或治疗感染的人多克隆抗体组合物含有人多克隆抗体，其通过作为免疫原将细菌和/或病毒或细菌和/或病毒的成分施用于具有人抗体的非人动物获得 并且对细菌和/或病毒的抗体滴度超过人池血浆的抗体滴度。