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    Polymer thin film, its production method, binder for bio chip, bio chip, and its production method
    1.
    发明公开
    Polymer thin film, its production method, binder for bio chip, bio chip, and its production method 有权
    薄的聚合物层，制造过程中，对于有机芯片，生物芯片和过程及其制备粘合剂

    公开(公告)号：EP1260542A1

    公开(公告)日：2002-11-27

    申请号：EP02253423.4

    申请日：2002-05-16

    申请人： Kishimoto Sangyo Co., Ltd.

    发明人： Nakamura, Eiichi, c/o Kishimoto Sangyo Co. Ltd. ,  Shibayama, Kenichi, c/o Kishimoto Sangyo Co. Ltd. ,  Maruyama, Hiroshi, c/o Daisankasei Co., Ltd. ,  Inoue, Takashi, c/o Daisankasei Co., Ltd.

    IPC分类号： C08J5/18 ,  C08G61/02 ,  C09D165/04 ,  C12Q1/68 ,  B05D7/24

    CPC分类号： B05D1/60 ,  C08G61/02 ,  C08G61/025 ,  C08G2261/3424 ,  C08J5/18 ,  C08J2365/04 ,  Y10T428/29 ,  Y10T428/31504

    摘要： This invention provides a polymer thin film which is useful as a substrate for immobilizing a histocompatibility-imparting agent, an immunosuppressive agent, a bioreaction suppressive agent, or the like, and which can be used in imparting biocompatibility; its production method; a binder for a bio chip wherein loss of probe and sample substances in the washing step has been reduced to realize efficient use of such probe and sample; and its production method. In the present invention, the starting material represented by the following structural formula (I) is evaporated and heated to bring the material into monomer form. The material is then introduced into a vacuum deposition chamber maintained at a predetermined degree of vacuum wherein the material is deposited and polymerized on a substrate to obtain the polymer thin film. This polymer thin film is also used in producing the bio chip.
    wherein R 11 and R 12 independently represent -CH 2 NH 2 group or H, and at least one of the R 11 and R 12 is -CH 2 NH 2 group.

    摘要翻译： 本发明提供一种聚合物薄膜，其全部作为用于固定组织相容性赋予剂，免疫抑制剂，生物反应抑制剂，或类似的一个基板是有用的，并且可以在赋予生物相容性使用; 其生产方法; 对于在洗涤步骤中的样品和样品的物质的生物芯片worin损失的粘结剂已降低到实现高效利用搜索探针和样品的; 及其制造方法。 在本发明中，由以下结构式（I）表示的起始原料被蒸发并加热到使材料成单体形式。然后将该材料引入保持在预定的真空度的真空沉积腔室worin所述材料是 沉积并聚合在衬底以得到聚合物薄膜。 因此，该聚合物薄膜是用来在生产生物芯片。 worin R11和R12表示-CH 2 NH 2unabhängig基或H，和R 11中的至少一个，并且R 12是-CH 2 NH 2基团。