公开(公告)号：EP0460232A4

公开(公告)日：1993-03-17

申请号：EP91900944

申请日：1990-12-21

申请人： KOKEN LTD.

发明人： IIJIMA, KUNIHITO ,  KATO, HARUKI ,  NAGASU, YOICHIRO

IPC分类号： A61K31/765 ,  A61K9/00 ,  A61K31/215 ,  A61K31/22 ,  A61K38/00 ,  A61K38/02 ,  A61K38/04 ,  A61K47/02 ,  A61K47/10 ,  A61K47/26 ,  A61K47/34 ,  A61P35/00 ,  A61K37/02

CPC分类号： A61K9/0019 ,  A61K38/04 ,  A61K47/26 ,  A61K47/34 ,  A61K31/765 ,  A61K2300/00

摘要： A tumor cell growth inhibitor which comprises 10 parts by weight of a low condensate and polymer of an α-hydroxy acid, 1 to 4 parts by weight of an oligopeptide containing at least one pyroglutamic acid residue, and 1 to 3 parts by weight of a stabilizer. Said α-hydroxy acid condensate and polymer mainly comprise a condensate of 2 to 10 molecules of an α-hydroxy acid, a polymer thereof, and metal salts thereof; said oligopeptide comprises an oligopeptide composed of 2 to 8 amino acid residues and containing at least one pyroglutamic acid residue and metal salts thereof; and said stabilizer comprises a sugar and a sugar alcohol.