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    EXTRACTS OF ASTER KORAIENSIS, AND PHARMACEUTICAL COMPOSITION AND FUNCTIONAL FOOD COMPRISING THE SAME
    4.
    发明公开
    EXTRACTS OF ASTER KORAIENSIS, AND PHARMACEUTICAL COMPOSITION AND FUNCTIONAL FOOD COMPRISING THE SAME 有权
    FROM ASTER红松提取物和含有药物组合物和功能性食品

    公开(公告)号：EP2131850A4

    公开(公告)日：2011-06-15

    申请号：EP08723329

    申请日：2008-03-07

    申请人： KOREA INST ORIENTAL MEDICINE

    发明人： KIM JIN SOOK ,  JANG DAE SIK ,  LEE YUN MI ,  KIM JONG MIN ,  KIM YOUNG SOOK ,  SHON EUN JIN ,  KIM CHAN SIK ,  KIM JUNG HYUN ,  KIM OHN SOON ,  JUNG DONG HO ,  YOO JEONG LIM ,  KIM JOO HWAN

    IPC分类号： A61K36/28 ,  A61P3/10

    CPC分类号： A61K36/28 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/328 ,  A23V2250/21

    摘要： Disclosed herein are a leaf and stem extract of Aster koraiensis, a root extract of Aster koraiensis, a flower extract of Aster koraiensis, a pharmaceutical composition for the prevention or treatment of diabetic complications, a health functional food for the improvement of diabetic complications, and a pharmaceutical composition and health functional food for the prevention or delay of aging, in which each of the compositions and the foods contain, as an active ingredient, at least one of said Aster koraiensis extracts. Each of the extracts is obtained by drying and finely cutting each of the leaf and stem part, root and flower of Aster koraiensis, extracting the cut plant with alcohol or aqueous alcohol solution, filtering the extracted solution and concentrating the filtrate under reduced pressure. Also disclosed are a pharmaceutical composition for the prevention or treatment of diabetic complications, a health functional food for the improvement of diabetic complications, and a pharmaceutical composition and health functional food for the prevention or delay of aging, which contain, as an active ingredient, at least one of fractions obtained by fractionating each of said Aster koraiensis extracts in the order of hexane, ethyl acetate, n-butanol and water fractions. The leaf and stem extract of Aster koraiensis, the root extract of Aster koraiensis and the flower extract of Aster koraiensis have the effect of inhibiting the production of advanced glycation endproducts (AGEs), the causes of diabetic complications, and effectively inhibit aldose redductase (AR) activity. Thus, the disclosed extracts will be highly useful for the prevention or treatment of diabetic complications and the prevention of aging.