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公开(公告)号：EP3954392A1
公开(公告)日：2022-02-16
申请号：EP19924243.9
申请日：2019-12-17
发明人： KANG, Il-Mo , LEE, Jangik lke , KIM, Dae-Duk , KIM, Jae Hwan , ROH, Ki-Min , SEO, Sung Man , JUNG, Su Young , PARK, Ju-Hwan , BAEK, Min-Jun , KIM, Gyu-Ho
IPC分类号： A61K47/52 , A61K31/444 , A61K9/00
摘要： The present invention relates to a composition for oral administration with controlled release properties, comprising a complex of a compound of Chemical Formula 1 or a pharmaceutically acceptable salt thereof; and a clay mineral, and a method for preparing same.
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公开(公告)号：EP3988119A1
公开(公告)日：2022-04-27
申请号：EP20827931.5
申请日：2020-05-22
发明人： KIM, Jae Hwan , KANG, Il-Mo , SONG, Young Goo , ROH, Ki Min , SONG, Yungoo , SEO, Sung Man , KIM, Dae Young
IPC分类号： A61K47/52 , A61K9/00 , A61K31/7036 , A61K45/06 , A61P31/04
摘要： Disclosed is an orally-administered pharmaceutical composition or kit for eradicating Helicobacter pylori comprising a complex of a non-absorbable antibiotic and a clay mineral. The pharmaceutical composition or kit of the present disclosure may further comprise a β-lactam antibiotic and/or a gastric acid-suppressive agent.
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公开(公告)号：EP3954391A1
公开(公告)日：2022-02-16
申请号：EP19923918.7
申请日：2019-12-17
发明人： KANG, Il-Mo , LEE, Jangik lke , KIM, Dae-Duk , KIM, Jae Hwan , ROH, Ki-Min , SEO, Sung Man , JUNG, Su Young , PARK, Ju-Hwan , BAEK, Min-Jun , KIM, Gyu-Ho
IPC分类号： A61K47/52 , A61K31/444 , A61K9/00 , A61P1/04 , A23L33/10 , A23L33/165
摘要： The present invention relates to a pharmaceutical composition for prevention, alleviation, and treatment of inflammatory bowel disease, the composition comprising a complex of a compound of Chemical Formula 1 or a pharmaceutically acceptable salt thereof and a clay mineral; a method for prevention, alleviation, and treatment of inflammatory bowel disease by using same; and a preparation method of the pharmaceutical composition.
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公开(公告)号：EP3738583A1
公开(公告)日：2020-11-18
申请号：EP19739175.8
申请日：2019-03-08
发明人： KANG, Il Mo , KIM, Dae Duk , PARK, Ju Hwan , ROH, Ki Min , LEE, Jang Ike , KIM, Jae Hwan , SEO, Sung Man , JUNG, Su Young
摘要： A drug and layered silicate composite is provided. The drug and layered silicate contains layered silicate powders; and a drug compound bound to between layers of the silicate powders, wherein the drug compound is present in an amorphous state in the composite. Using such a composite may significantly improve absorption and bioavailability of a sorafenib compound.
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5.发明公开
公开(公告)号：EP4265262A1
公开(公告)日：2023-10-25
申请号：EP21907162.8
申请日：2021-12-17
发明人： KANG, Il Mo , KWAK, Jin Hwan , KIM, Daniel , ROH, Ki Min , KIM, Jae Hwan , SEO, Sung Man , KIM, Dae Young
摘要： The present invention relates to a pharmaceutical composition for treating Clostridioides difficile Infection (CDI), and a method for producing same. The pharmaceutical composition comprises a complex of clay minerals, such as bentonite, and antibiotics, such as vancomycin. Accordingly, the pharmaceutical composition has an excellent treatment effect on CDI even with a significantly smaller amount of each of the existing antibiotics and clay minerals than the maximum recommended daily intake thereof, and has the effect of reducing side effects that can be caused by the massive intake of the antibiotics and clay minerals.
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6.发明公开
公开(公告)号：EP4176903A1
公开(公告)日：2023-05-10
申请号：EP21832931.6
申请日：2021-07-01
发明人： KIM, Jae Hwan , KANG, Il Mo , KIM, Dae Duk , LEE, Jang Ik , KIM, Gyu Ho , BAEK, Min Jun , PARK, Chang Yun , ROH, Ki Min , SEO, Sung Man
IPC分类号： A61K47/54 , A61K47/52 , A61K31/554 , A61K31/496 , A61K31/337 , A61K31/4745 , A61K31/55 , A61K31/517 , A61K31/5513 , A61K31/519
摘要： According to one embodiment of the present invention, provided is a drug-clay mineral complex, in which the complex comprises a phospholipid, and the drug has an amine group.
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