公开(公告)号：EP1924159A4

公开(公告)日：2010-10-20

申请号：EP06783327

申请日：2006-07-18

申请人： KOREA RES INST OF BIOSCIENCE

发明人： LEE HYEONG KYU ,  OH SEI RYANG ,  AHN KYUNG SEOP ,  LEE JOONG KU ,  LEE SAN KU ,  KIM JUNG HEE ,  KIM DOO YOUNG ,  QUAN GUI HUA ,  KWON OK KYOUNG ,  KIM EUN AH ,  CHOI SOON JA ,  SHEN GUANG HAI ,  KIM MI JIN ,  PARK BO YOUNG ,  MIN BYUNG SUN ,  HAN GYOON HEE ,  PARK HEA YOUNG ,  KIM GUN CHEOL ,  KIM JOO HEON ,  KIM SO YOUNG

IPC分类号： A61K36/185 ,  A23L33/00 ,  A61P37/08

CPC分类号： A61K36/185 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/304

摘要： The present invention relates to a composition comprising an extract of Tiarella polyphylla, and tiarellic acid isolated therefrom having anti-inflammatory, anti-allergic and anti-asthmatic activity. The extract of Tiarella polyphylla and the tiarellic acid isolated therefrom shows the inhibitory effect on the LTC 4 release in vitro test and the suppressive effect on the IgE level and the cytokine(IL-4, IL-5 and IL- 13) production, airway hyperresponsiveness, and leukocyte infiltration in OVA-induced asthmatic mice. Therefore, it can be used as the therapeutics or functional health food for treating and preventing inflammatory, allergic and asthmatic disease.