专利检索 ap:("KRKA, d.d., Novo mesto") AND inv:"Andolsek, Barbara" 第 1 页

1.

发明公开
RACEMIZATION OF (S) AND/OR (R)-3-(DIMETHYLAMINO)-1-(3-METHOXYPHENYL)-2-METHYLPROPAN-1- ONE AND ITS MIXTURES 审中-公开

公开(公告)号：EP4116288A1

公开(公告)日：2023-01-11

申请号：EP21184477.4

申请日：2021-07-08

申请人： KRKA, d.d., Novo mesto

发明人： Bezensek, Jure , Andolsek, Barbara

IPC分类号： C07C213/00 , C07C213/08 , C07C221/00 , C07C225/16 , C07C217/72 , C07C217/62

摘要： The present invention provides means and methods for synthesizing tapentadol with increased yield. The processes of the present invention involve a step of racemization of (R)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one.