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公开(公告)号：EP0152076B1
公开(公告)日：1990-05-16
申请号：EP85101354.0
申请日：1985-02-08
IPC分类号： C12N15/00 , C12P21/02 , C07K15/00 , C12N1/20 , G01N33/535
CPC分类号： C07K14/005 , C07K2319/00 , C07K2319/40 , C07K2319/61 , C12N2740/14022 , Y10S530/806 , Y10S530/808 , Y10S530/82 , Y10S530/825
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公开(公告)号：EP0121157A1
公开(公告)日：1984-10-10
申请号：EP84102712.1
申请日：1984-03-13
摘要： Disclosed is a novel human interferon-y polypeptide, a recombinant plasmid wherein a DNAfragment coding forthe polypeptide is incorporated, and a process for producing the human interferon-y polypeptide using a microorganism containing the plasmid.
摘要翻译： 公开了一种新型人类干扰素-γ多肽，其中掺入编码多肽的DNA片段的重组质粒，以及使用含有该质粒的微生物生产人类干扰素-γ多肽的方法。
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3.发明公开Recombinant plasmid containing human interferon-beta gene 失效重组质粒menschliches beta-Interferon Gen enthaltend。
公开(公告)号：EP0083069A2
公开(公告)日：1983-07-06
申请号：EP82111895.7
申请日：1982-12-22
发明人： Itoh, Seiga , Nishi, Tatsunari , Mizukami, Tamio , Matsumoto, Tadashi , Oka, Tetsuo , Taniguchi, Tadatsugu , Sugano, Haruo
CPC分类号： C07K14/565 , C12N15/71 , Y10S930/142
摘要： Disclosed are recombinant vector plasmids containing a DNA fragment coding for human interferon-β inserted downstream from a tryptophane promoter. The plasmids are useful for transformation of microorganisms such as Escherichia coli which transformants produce human interferon-β.
摘要翻译： 公开了含有编码从色氨酸启动子下游插入的人干扰素-β的DNA片段的重组载体质粒。 质粒可用于转化微生物如转化体产生人干扰素-β的大肠杆菌。
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公开(公告)号：EP0152076A3
公开(公告)日：1986-08-13
申请号：EP85101354
申请日：1985-02-08
IPC分类号： C12N15/00 , C12P21/02 , C07K15/00 , C12N01/20 , G01N33/535
CPC分类号： C07K14/005 , C07K2319/00 , C07K2319/40 , C07K2319/61 , C12N2740/14022 , Y10S530/806 , Y10S530/808 , Y10S530/82 , Y10S530/825
摘要： Recombinant plasmids are constructed by inserting a DNA fragment coding for a fused protein of an adult T cell leukemia virus antigen peptide and an enzyme into a vector DNA. Microorganisms are transformed with the recombinant . plasmid and thereafter cultured to express the fused protein. The fused protein is useful for the detection and diagnosis of adult T cell leukamia.
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5.发明公开Derivative of adult T cell leukemia virus antigen peptide 失效Derivat des Adult-T-Zell-Leukemiavirus-Antigenpeptids。
公开(公告)号：EP0152076A2
公开(公告)日：1985-08-21
申请号：EP85101354.0
申请日：1985-02-08
IPC分类号： C12N15/00 , C12P21/02 , C07K15/00 , C12N1/20 , G01N33/535
CPC分类号： C07K14/005 , C07K2319/00 , C07K2319/40 , C07K2319/61 , C12N2740/14022 , Y10S530/806 , Y10S530/808 , Y10S530/82 , Y10S530/825
摘要： Recombinant plasmids are constructed by inserting a DNA fragment coding for a fused protein of an adult T cell leukemia virus antigen peptide and an enzyme into a vector DNA. Microorganisms are transformed with the recombinant . plasmid and thereafter cultured to express the fused protein. The fused protein is useful for the detection and diagnosis of adult T cell leukamia.
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公开(公告)号：EP0121157B1
公开(公告)日：1989-06-14
申请号：EP84102712.1
申请日：1984-03-13
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公开(公告)号：EP0083069A3
公开(公告)日：1984-03-28
申请号：EP82111895
申请日：1982-12-22
发明人： Itoh, Seiga , Nishi, Tatsunari , Mizukami, Tamio , Matsumoto, Tadashi , Oka, Tetsuo , Taniguchi, Tadatsugu , Sugano, Haruo
CPC分类号： C07K14/565 , C12N15/71 , Y10S930/142
摘要： Disclosed are recombinant vector plasmids containing a DNA fragment coding for human interferon-β inserted downstream from a tryptophane promoter. The plasmids are useful for transformation of microorganisms such as Escherichia coli which transformants produce human interferon-β.
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公开(公告)号：EP0083069B1
公开(公告)日：1987-09-16
申请号：EP82111895.7
申请日：1982-12-22
发明人： Itoh, Seiga , Nishi, Tatsunari , Mizukami, Tamio , Matsumoto, Tadashi , Oka, Tetsuo , Taniguchi, Tadatsugu , Sugano, Haruo
CPC分类号： C07K14/565 , C12N15/71 , Y10S930/142
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公开(公告)号：EP0502448A3
公开(公告)日：1993-01-20
申请号：EP92103486.4
申请日：1992-02-28
发明人： Satoh, Mitsuo , Miyaji, Hiromasa , Sato, Seiji , Itoh, Seiga
IPC分类号： G01N33/68 , G01N33/564 , G01N33/574
CPC分类号： G01N33/564 , C07K16/00 , G01N2800/104
摘要： A method of assaying anti-ubiquitin antibody is provided which comprises allowing anti-ubiquitin antibody in a sample to bind to polyubiquitin supported on a solid phase, then allowing a labeled anti-human immunoglobulin specific antibody to bind to the bound anti-ubiquitin antibody, and assaying the label on said specific antibody.
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公开(公告)号：EP0267622A3
公开(公告)日：1991-01-30
申请号：EP87116787.0
申请日：1987-11-13
发明人： Fukui, Masanori , Kuga, Tetsuro , Yamasaki, Motoo , Itoh, Seiga
IPC分类号： G01N33/569 , G01N33/552
CPC分类号： C07K14/005 , C12N2740/14022 , G01N33/56988
摘要： The present invention provides a method for detecting an anti-adult T cell leukemia virus antibody in a sample according to an immunological procedure using a polypeptide encoded by a fused gene comprising the gag gene of ATLV or a part thereof and the env gene of ATLV or a part thereof as an antigenic substance.
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