公开(公告)号：EP1308509A4

公开(公告)日：2004-05-12

申请号：EP01955553

申请日：2001-08-01

申请人： KYOWA HAKKO KOGYO KK

发明人： SATOH MITSUO ,  SHIBATA KENJI ,  SEKINE SUSUMU ,  KOIKE MASAMICHI ,  SAKURAI WATARU ,  FURUYA AKIKO ,  MORI KATSUHIRO ,  KATO YOKO

IPC分类号： A61K38/00 ,  A61K48/00 ,  A61P1/00 ,  A61P3/10 ,  A61P9/00 ,  A61P9/08 ,  A61P9/10 ,  A61P11/06 ,  A61P13/12 ,  A61P17/06 ,  A61P19/02 ,  A61P25/02 ,  A61P27/06 ,  A61P27/14 ,  A61P27/16 ,  A61P35/00 ,  A61P37/06 ,  A61P37/08 ,  C07K14/47 ,  C07K14/52 ,  C12P21/08 ,  C12N15/09 ,  A61K39/00

CPC分类号： C07K14/52 ,  A01K2217/075 ,  A61K38/00 ,  A61K48/00 ,  C07K14/47

摘要： A physiologically active peptide which is useful in searching for and developing remedies for diseases accompanying infection or inflammation, diseases accompanying abnormal differentiation and proliferation of smooth muscle cells, diseases accompanying abnormal activation of fibroblasts, diseases accompanying abnormal activation of synovial tissues, diseases accompanying disorders in pancreatic ss cells, diseases accompanying disorders in osteoblasts or osteoclasts, diseases accompanying abnormal activation of immunocytes, diseases accompanying vascular disorders, eye diseases based on abnormal angiogenesis, diseases accompanying abnormal cell proliferation, diseases in association with the major histocompatible antigen gene domain, etc.; DNA encoding this peptide; an antibody recognizing this peptide; and methods of using the same.