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公开(公告)号：EP2365908A2
公开(公告)日：2011-09-21
申请号：EP09833025.1
申请日：2009-11-16
发明人： HOFFMAN, Douglas, Robert , SMILTNEEK, Andrea, Jo , CARNEY, Sara, Ann , WENZEL, Scott, W. , KOENIG, David, William , SEIDLING, Jeffery, Richard
CPC分类号： A61K9/7007 , A61K9/0024 , A61K31/00 , A61L15/22 , A61L15/44 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/61
摘要： The present disclosure comprises a polymeric substrate that provides multiple releases of active agents. A substrate for multiple phase delivery of active agents is provided having a first polymer matrix layer having a first active agent disposed therein, a second polymer matrix layer having a second active agent disposed therein, and a coacervate layer disposed between the first polymer matrix layer and the second polymer matrix layer. Selected first and second active agents are included in the first and second polymer matrices such that as the first and second polymer matrices dissolve, the active agents are released. Multiple phase active agent release is achieved by constructing multiple layers of a polymer matrix containing an active agents formed with polymers having different solubility characteristics or with active agents at different concentration levels.
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2.发明公开ULTRASONIC TREATMENT CHAMBER FOR INCREASING THE SHELF LIFE OF FORMULATIONS 审中-公开超声波发光二极管ZURERHÖHUNGDER HALTBARKEIT VON FORMULIERUNGEN UND VERFAHREN DAZU
公开(公告)号：EP2227323A2
公开(公告)日：2010-09-15
申请号：EP08868678.7
申请日：2008-12-23
发明人： KOENIG, David, William , AHLES, John, Glen , EHLERT, Thomas, David , JANSSEN, Robert, Allen , RASMUSSEN, Paul, Warren , ROFFERS, Steve , WENZEL, Scott W. , ZHUANG, Shiming
CPC分类号： B01D19/0094 , B01D19/0078
摘要： An ultrasonic treatment system having a treatment chamber for treating a formulation to increase the shelf life thereof. In one embodiment, the shelf life is produced by degassing the formulation using the treatment chamber. Specifically, the treatment chamber has an elongate housing through which a formulation flows longitudinally from an inlet port to a first outlet port and a second outlet port thereof. An elongate ultrasonic waveguide assembly extends within the housing and is operable at a predetermined ultrasonic frequency to ultrasonically energize the formulation within the housing. An elongate ultrasonic horn of the waveguide assembly is disposed at least in part intermediate the inlet and outlet ports, and has a plurality of discrete agitating members in contact with and extending transversely outward from the horn intermediate the inlet and outlet ports in longitudinally spaced relationship with each other. The horn and agitating members are constructed and arranged for dynamic motion of the agitating members relative to the horn at the predetermined frequency and to operate in an ultrasonic cavitation mode of the agitating members corresponding to the predetermined frequency and the formulation being treated in the chamber.
摘要翻译： 一种超声处理系统，具有用于处理制剂以增加其保质期的处理室。 在一个实施方案中，通过使用处理室对制剂进行脱气而产生保质期。 具体地说，处理室具有细长的外壳，制剂通过该外壳纵向从入口端口流向第一出口和第二出口。 细长的超声波波导组件在壳体内延伸并且可以预定的超声波频率操作以超声波地激励壳体内的配方。 波导组件的细长的超声波喇叭至少部分地设置在入口和出口的中间，并且具有多个离散的搅拌构件，其与入口和出口端口处的喇叭中的接触并横向向外延伸，与纵向间隔开的关系与 彼此。 喇叭和搅拌构件被构造和布置成用于以预定频率相对于喇叭的搅动构件的动态运动，并且在对应于预定频率的搅拌构件的超声空化模式和在室中处理的配方中操作。
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公开(公告)号：EP1455852B1
公开(公告)日：2008-02-13
申请号：EP02778691.2
申请日：2002-10-30
IPC分类号： A61L15/46
CPC分类号： A61L15/46 , A61L31/127 , A61L2300/208 , A61L2300/404 , A61L2300/62 , Y10T428/249972 , Y10T442/2525 , C08L67/04
摘要： Absorbent products and wet wipes are disclosed that are useful in reducing the amount of ammonia produced by bacteria on or near the skin or in bodily fluids such as urine. The products described herein contain an osmoregulation protector which when introduced into a bacteria-containing environment interacts with the bacteria and reduces the amount of ammonia produced by the bacteria without significantly affecting the growth rate of the bacteria. The osmoregulation protectors described herein are particularly useful in combination with adult incontinence garments where the control of odors from bacterial by-products such as ammonia is highly desirable.
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公开(公告)号：EP1587949A2
公开(公告)日：2005-10-26
申请号：EP04706995.0
申请日：2004-01-30
发明人： BAGWELL, Alison, S. , JOHNSON, David, W. , KOENIG, David, William , SHAMIS, Martin, S. , TRUSCOTT, Wava
CPC分类号： C08J7/047 , A41D19/0058 , A41D2400/34 , A61B42/00 , C08J2321/00 , C08J2483/00 , Y10T428/31663 , Y10T442/2525
摘要： An elastomeric article having reducing microbe affinity and transmission is disclosed. The article includes an exterior surface including an antimicrobial polymer, where the antimicrobial polymer is formed from an organosilane quaternary ammonium compound.
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公开(公告)号：EP3831391A1
公开(公告)日：2021-06-09
申请号：EP21150997.1
申请日：2015-09-29
发明人： LI, Jingru , PEED, Lindsay, Adrienne , JOYNER, Cheryce, Francina , VONGSA, Rebecca, Ann , KOENIG, David, William , BARTELL, Ryan, Daniel
IPC分类号： A61K31/7016 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61P15/02
摘要： The present invention provides compositions and formulations capable of maintaining or promoting the growth of certain strains of Lactobacilli spp. The compositions and formulations comprise isomaltulose The compositions have been shown to promote the growth and maintenance of beneficial lactobacilli and to effectively inhibit the growth of pathogens associated with urogenital infections. As such administration of the compositions maintain a healthy microflora balance in the urogenital area.
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公开(公告)号：EP1943302A2
公开(公告)日：2008-07-16
申请号：EP06824863.2
申请日：2006-08-31
发明人： SCHORR, Phillip, A. , HOFFMAN, Douglas, R. , KOENIG, David, William , SPENCER, Anthony, S. , YAHIAOUI, Ali , DOBSON, Angela, G.
CPC分类号： A01N47/44 , C08K5/0058 , D06M15/564 , D06M15/61 , D06M16/00 , A01N25/10 , A01N25/34 , A01N33/12 , A01N37/02 , A01N37/04 , A01N37/36 , A01N59/00 , A01N2300/00 , C08L21/00
摘要： A material substrate having at least part of a surface treated with an antimicrobial composition is described. The antimicrobial composition exhibits at least a 3 log10 CFU reduction within a period of about 30 minutes after contact with various species of a broad spectrum of microorganisms. The substrate can be a nonwoven material that has good fluid barrier properties, which can be used in protective garments and sheets. Methods for manufacturing and imparting the antimicrobial treatment to the substrate are also provided.
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公开(公告)号：EP1919282A2
公开(公告)日：2008-05-14
申请号：EP06824867.3
申请日：2006-08-31
发明人： SCHORR, Phillip, A. , YAHIAOUI, Ali , HOFFMAN, Douglas, R. , KOENIG, David, William , SPENCER, Anthony, S. , DOBSON, Angela, G.
CPC分类号： A01N25/34 , A01N47/44 , A41D13/11 , A41D2400/34 , A61B17/00 , A61K31/785 , A61L31/16 , A61L2300/416 , A61L2300/606 , A01N2300/00
摘要： A synergistic antimicrobial composition containing at least two kinds of antimicrobial agents, including poly-hexamethylene biguanide (PHMB), stably associated to a material substrate is described. The substrate can take the forms of an anti-infection face mask, medical devices, or surgical instruments.
摘要翻译： 描述了一种协同抗微生物组合物，其含有至少两种抗微生物剂，包括与材料基质稳定缔合的聚六亚甲基双胍（PHMB）。 底物可以采取抗感染面罩，医疗设备或手术器械的形式。
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公开(公告)号：EP1827512A2
公开(公告)日：2007-09-05
申请号：EP05852941.3
申请日：2005-12-02
摘要： The present invention relates to methods for minimizing the presence of microbial pathogens on currency or on mail. More particularly, the presence of microbial pathogens may be minimized by introducing an antimicrobial product comprising a base substrate and a volatile and/or non-volatile antimicrobial agent into a money container comprising currency or into an envelope. The antimicrobial agent may be either transferred directly to the currency or envelope by contacting the antimicrobial product with the currency or envelope, or through permeation of the volatile antimicrobial throughout the money container or envelope.
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9.发明公开METHOD OF MAKING FIBERS, NONWOVEN FABRICS, POROUS FILMS AND FOAMS THAT INCLUDE SKIN TREATMENT ADDITIVES 审中-公开用于生产纤维，非织造材料，多孔膜和波光粼粼的，每一个额外的材料含有HAUTBEHANLUNG
公开(公告)号：EP1572048A2
公开(公告)日：2005-09-14
申请号：EP03781699.8
申请日：2003-11-03
发明人： FENWICK, Christopher, Dale , HAYNES, Bryan, David , PAUL, Susan, Carol , YAHIAOUI, Ali , SHARMA, Varunesh , TYRRELL, David, John , MINERATH, Bernard, Joseph , KRZYSIK, Duane, Gerard , KOENIG, David, William , MAJORS, Mark, Bruce , POLANCO, Braulio, Arturo , LAKE, Matthew, Boyd , BROCK, Earl, David
CPC分类号： D06M23/06 , A61F13/8405 , A61K8/0208 , A61K8/63 , A61K8/891 , A61Q19/00 , D01F1/10 , D01F8/06 , D04H13/00 , D06M11/79 , D06M23/08 , Y10T442/20 , Y10T442/2861 , Y10T442/699
摘要： The present invention provides fibers, foams, films and nonwoven fabrics having more than one skin treatment benefit and/or improved skin treatment benefit(s) and to products incorporated such fibers, foams, films and fabrics . The present invention also provides a method of forming fibers, nonwoven fabrics, porous films and foams having multiple skin treatment benefits.
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公开(公告)号：EP2200937B1
公开(公告)日：2018-10-10
申请号：EP08789393.9
申请日：2008-07-21
IPC分类号： C01B33/148 , C01B33/20 , C01G29/00 , C08J3/12 , B82B1/00 , C01B33/14 , D21H17/67 , A61K8/02 , A61Q1/12
CPC分类号： A61Q1/12 , A61K8/0245 , A61K2800/412 , B82Y30/00 , C01B33/14 , C01P2004/12 , C01P2004/16 , C01P2004/54 , C01P2004/62 , C01P2004/64 , D21H23/22 , Y10T428/25 , Y10T428/256 , Y10T428/257
摘要： The present disclosure is generally directed to a composition comprising one or more elongated particles having a diameter of from about 5 nm to about 500 nm, a length that is greater than the diameter and an aspect ratio of greater than about 1. The aspect ratio affects the orientation of such elongated particles in relation to a surface on which the composition is applied.
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