公开(公告)号：EP4286515A1

公开(公告)日：2023-12-06

申请号：EP22746252.0

申请日：2022-01-27

申请人： Korea Advanced Institute of Science and Technology

发明人： LEE, Sang Yup ,  YANG, Dongsoo ,  JANG, Woo Dae

IPC分类号： C12N9/10 ,  C12N9/00 ,  C12N9/12 ,  C12N9/02 ,  C12N15/70 ,  C12P19/04

摘要： The present invention relates to novel C-glycosyltransferase variants and a use thereof. The C-glycosyltransferase variants according to the present invention have improved glycosidic bond-forming ability as compared with wild-type C-glycosyltransferase, and thus can increase the glycoside production effects of polyketide groups and pseudo-natural products, particularly type I, II, III polyketide, nonribosomal peptides, phenylpropanoids, and other aromatic natural products, and thus can be useful for the preparation of a drug, a food additive, a nutritional supplement, and the like containing a C-glycoside compound as a constituent ingredient.