公开(公告)号：EP3703134A1

公开(公告)日：2020-09-02

申请号：EP18871738.3

申请日：2018-10-29

申请人： Korea Research Institute of Bioscience and Biotechnology

发明人： KWON, Oh Seok ,  LEE, Chang Soo ,  PARK, Seon Joo ,  HA, Tai Hwan ,  PARK, Chul Soon ,  KIM, Kyung Ho ,  KIM, Jin Yeong

IPC分类号： H01L29/16 ,  H01L29/772 ,  H01L29/66 ,  H01L21/324 ,  H01L21/02 ,  H01L51/00

摘要： The present invention relates to a graphene transistor comprising: a substrate; a graphene channel layer arranged on the substrate; a pair of metals spaced from each other and respectively arranged at opposite ends of the graphene channel layer; and a linker layer arranged on the graphene channel layer and including an N-heterocyclic carbene compound, a fabrication method therefor, and a biosensor comprising the same. The graphene transistor according to the present invention in which the carbene group of the N-heterocyclic carbene compound forms a covalent bond with the graphene channel layer to modify the whole surface of the graphene channel layer exhibits excellent electric conductivity as a transistor and a biosensor comprising the transistor is improved in selectivity and sensitivity.

公开(公告)号：EP3821982A1

公开(公告)日：2021-05-19

申请号：EP19834598.5

申请日：2019-07-12

申请人： Korea Research Institute of Bioscience and Biotechnology

发明人： KWON, Oh Seok ,  HA, Tai Hwan ,  KIM, Kyung Ho ,  KIM, Jin Yeong ,  PARK, Seon Joo ,  SEO, Seong Eun

IPC分类号： B01L7/00 ,  B01J19/00

摘要： The present invention relates to a substrate for nucleic acid amplification, and a method for manufacturing same, the substrate for rapid and accurate PCR analysis comprising: a transparent substrate; a metal layer formed on the transparent substrate; an N-heterocyclic carbene compound having one end annealed to the surface of the metal layer; and a primer immobilized on the other end of the N-heterocyclic carbene compound.

公开(公告)号：EP3821981A1

公开(公告)日：2021-05-19

申请号：EP19834182.8

申请日：2019-07-12

申请人： Korea Research Institute of Bioscience and Biotechnology

发明人： KWON, Oh Seok ,  HA, Tai Hwan ,  KIM, Kyung Ho ,  KIM, Jin Yeong ,  PARK, Seon Joo ,  SEO, Seong Eun

IPC分类号： B01L7/00 ,  B01J19/00

摘要： The present invention relates to a substrate for nucleic acid amplification, and a method for manufacturing same, the substrate for rapid and accurate PCR analysis comprising: a transparent substrate; a micro-patterned metal layer formed on the transparent substrate; an N-heterocyclic carbene compound having one end annealed to the surface of the micro-patterned metal layer; and a primer immobilized on the other end of the N-heterocyclic carbene compound.

公开(公告)号：EP1909745A1

公开(公告)日：2008-04-16

申请号：EP06715944.2

申请日：2006-02-13

申请人： Korea Research Institute of Bioscience and Biotechnology

发明人： JUNG, Bong Hyun ,  LIM, Yong Taik ,  KIM, Jin Kyeong ,  JEONG, Jin Young ,  HA, Tai Hwan

IPC分类号： A61K8/19

CPC分类号： B82Y5/00 ,  A61K8/0241 ,  A61K8/19 ,  A61K8/8176 ,  A61K2800/413 ,  A61Q1/02 ,  A61Q1/06

摘要： The present invention relates to a cosmetic pigment composition exhibiting colors in the visible region, which comprises an effective amount of nanoparticles or a mixture of two or more nanoparticles selected from the group consisting of (a) gold nanoparticles exhibiting red color; (b) silver nanoparticles exhibiting yellow color; (c) gold-silver alloy nanoparticles exhibiting flame color; and (d) gold nanoparticles exhibiting blue color, and a color cosmetic composition and a color lotion comprising the pigment composition. According to the present invention, it is possible to prepare pigments exhibiting various colors in the visible region using gold or silver nanoparticles, and a cosmetic pigment composition which can exhibit various colors by mixing the pigments in various compositional ratios, in which precipitation or agglomeration of particles does not occur, and whose color can be maintained for a long time. Also, since the pigment of the present invention is not harmful to the human body unlike conventional metal pigments, and contains gold or silver that is beneficial to health, the pigment can be used in various applications as functional raw materials.

公开(公告)号：EP3885047A1

公开(公告)日：2021-09-29

申请号：EP19886397.9

申请日：2019-11-19

申请人： Korea Research Institute of Bioscience and Biotechnology

发明人： KWON, Oh Seok ,  KIM, Kyung Ho ,  PARK, Seon Joo ,  SEO, Seong Eun ,  HA, Tai Hwan

IPC分类号： B01L7/00 ,  B01L3/00

摘要： The present invention relates to a light-digital PCR chamber and a light-digital PCR device. The light-digital PCR chamber comprises: a transparent substrate; a metal thin film layer formed on the transparent substrate; a light shielding layer formed on the metal thin film layer; and a microchannel structure formed on the light shielding layer. The light-digital PCR device comprises a laminate comprising a transparent substrate, a metal thin film layer formed on the transparent substrate, and a light shielding layer formed on the metal thin film layer.