公开(公告)号：EP1715865B9

公开(公告)日：2010-12-15

申请号：EP05710692.4

申请日：2005-02-18

申请人： Kowa Company, Ltd. ,  Nissan Chemical Industries, Ltd.

发明人： AOKI, Taro ,  YAMAGUCHI, Junji ,  SASAKI, Yusuke

IPC分类号： A61K31/47 ,  A61K31/202 ,  A61P3/06

CPC分类号： A61K31/47 ,  A61K31/202 ,  A61K2300/00

摘要： Abstract The present invention relates to a hyperlipemia therapeutic agent comprising pitavastatins and eicosapentaenoic acid or an ester derivative thereof as effective ingredients. According to the present invention, a type IIb and type IV hyperlipemia therapeutic agent having an excellent effect of lowering the cholesterol and triglyceride in blood is provided.

摘要翻译： 摘要本发明涉及包含匹伐他汀和二十碳五烯酸或其酯衍生物作为有效成分的高脂血症治疗剂。 根据本发明，提供了具有降低血液中胆固醇和甘油三酯的优异效果的IIb型和IV型高脂血症治疗剂。

公开(公告)号：EP1715865B8

公开(公告)日：2010-05-19

申请号：EP05710692.4

申请日：2005-02-18

申请人： Kowa Company, Ltd. ,  Nissan Chemical Industries, Ltd.

发明人： AOKI, Taro ,  YAMAGUCHI, Junji ,  SASAKI, Yusuke

IPC分类号： A61K31/47 ,  A61K31/202 ,  A61P3/06

CPC分类号： A61K31/47 ,  A61K31/202 ,  A61K2300/00

摘要： Abstract The present invention relates to a hyperlipemia therapeutic agent comprising pitavastatins and eicosapentaenoic acid or an ester derivative thereof as effective ingredients. According to the present invention, a type IIb and type IV hyperlipemia therapeutic agent having an excellent effect of lowering the cholesterol and triglyceride in blood is provided.

公开(公告)号：EP1715865B1

公开(公告)日：2010-03-10

申请号：EP05710692.4

申请日：2005-02-18

申请人： Kowa Company. Ltd. ,  Nissan Chemical Industries, Ltd.

发明人： AOKI, Taro ,  YAMAGUCHI, Junji ,  SASAKI, Yusuke

IPC分类号： A61K31/47 ,  A61K31/202 ,  A61P3/06

CPC分类号： A61K31/47 ,  A61K31/202 ,  A61K2300/00

公开(公告)号：EP1715865A2

公开(公告)日：2006-11-02

申请号：EP05710692.4

申请日：2005-02-18

申请人： Kowa Company. Ltd. ,  Nissan Chemical Industries, Ltd.

发明人： AOKI, Taro ,  YAMAGUCHI, Junji ,  SASAKI, Yusuke

IPC分类号： A61K31/47 ,  A61K31/202 ,  A61P3/06

CPC分类号： A61K31/47 ,  A61K31/202 ,  A61K2300/00

摘要： Abstract The present invention relates to a hyperlipemia therapeutic agent comprising pitavastatins and eicosapentaenoic acid or an ester derivative thereof as effective ingredients. According to the present invention, a type IIb and type IV hyperlipemia therapeutic agent having an excellent effect of lowering the cholesterol and triglyceride in blood is provided.

公开(公告)号：EP1752145A1

公开(公告)日：2007-02-14

申请号：EP05743246.0

申请日：2005-05-27

申请人： Kowa Company. Ltd.

发明人： AOKI, Taro ,  YAMAGUCHI, Junji ,  SASAKI, Yusuke

IPC分类号： A61K31/192 ,  A61K31/22 ,  A61K31/366 ,  A61K31/40 ,  A61K31/404 ,  A61K31/47 ,  A61K31/505 ,  A61K45/00 ,  A61P3/06 ,  A61P3/10

CPC分类号： A61K31/404 ,  A61K31/192 ,  A61K31/22 ,  A61K31/366 ,  A61K31/40 ,  A61K31/47 ,  A61K31/505

摘要： A therapeutic agent for hyperlipidemia, diabetes, or hypertriglyceridemia containing an HMG-CoA reductase inhibitor and a carboxylic acid compound represented by the following formula (1) or a salt thereof as effective ingredients.

The therapeutic agent of the present invention has excellent effects of lowering blood cholesterol and blood triglycerides and is particularly useful for treatment of type IIb and type IV hyperlipidemia and treatment of diabetes and also useful for treatment of hypertriglyceridemia.

摘要翻译： 含有HMG-CoA还原酶抑制剂和由下式（1）表示的羧酸化合物或其盐作为有效成分的高脂血症，糖尿病或高甘油三酯血症的治疗剂。 本发明的治疗剂具有降低血液胆固醇和血液甘油三酸酯的优异效果，特别适用于治疗IIb型和IV型高脂血症和治疗糖尿病，也可用于治疗高甘油三酯血症。