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    Enteric-coated glucosinolates and beta-thioglucosidases
    1.
    发明公开
    Enteric-coated glucosinolates and beta-thioglucosidases 审中-公开
    葡萄糖硫酸葡萄糖苷和β-硫代葡萄糖苷类

    公开(公告)号：EP2065034A2

    公开(公告)日：2009-06-03

    申请号：EP08104379.6

    申请日：2008-06-11

    申请人： Kraft Foods Holdings, Inc.

    发明人： West, Leslie George ,  Windsor, Nicole Lee ,  Gaonkar, Anilkumar Ganapati ,  Matusheski, Nathan V. ,  Kim, Nam-Cheol ,  Ludwig, Cathy Jean ,  Lawrence, Leslie Lewis

    IPC分类号： A61K9/16 ,  A61K9/50

    CPC分类号： A61K9/1652 ,  A61K9/5063 ,  A61K31/375 ,  A61K31/7028 ,  A61K38/47 ,  A61K2300/00

    摘要： The present invention relates to a particulate composition comprising enteric-coated glucosinolate and beta-thioglucosidase particles. The present invention further provides a method of converting glucosinolate to isothiocyanate in the small intestine comprising orally administering to a subject an enteric-coated chemoprotectant precursor composition comprising enteric-coated glucosinolate and beta-thioglucosidase particles. In another aspect, uncoated glucosinolate and beta-thioglucosidase particles may be provided in an enteric-coated capsule. Preferably, the glucosinolate is glucoraphanin and the beta-thioglucosidase is myrosinase. The enteric coating targets the compound for release in the small intestine where beta-thiaglucosidase enzyme converts glucosinolate to chemoprotectant isothiocyanate.

    摘要翻译： 本发明涉及包含肠溶衣硫代葡萄糖苷苷和β-硫代葡萄糖苷酶颗粒的颗粒组合物。 本发明还提供了一种在小肠中将硫代葡萄糖苷转化为异硫氰酸酯的方法，其包括向受试者口服施用包含肠溶包衣的硫代葡萄糖苷和β-硫代葡糖苷酶颗粒的肠溶衣化学保护剂前体组合物。 在另一方面，可以在肠溶衣胶囊中提供未包衣的硫代葡萄糖苷和β-硫代葡萄糖苷酶颗粒。 优选地，硫代葡萄糖苷是葡萄糖甙元，β-硫代葡萄糖苷酶是黑芥子酶。 肠溶衣靶向化合物在小肠中释放，其中β-硫葡萄糖苷酶将硫代葡萄糖苷转化成化学保护剂异硫氰酸酯。

    Food modifier transferable article
    2.
    发明公开
    Food modifier transferable article 审中-公开
    食品改性剂可转移的文章

    公开(公告)号：EP1683734A1

    公开(公告)日：2006-07-26

    申请号：EP06100250.7

    申请日：2006-01-11

    申请人： KRAFT FOODS HOLDINGS, INC.

    发明人： Darin, Neil Edward ,  Ludwig, Cathy Jean ,  Gaonkar, Anilkumar Ganapati ,  Windsor, Nicole Lee

    IPC分类号： B65D65/46 ,  A23D9/00 ,  A23L1/01 ,  A23L1/00

    CPC分类号： A23D9/007

    摘要： The present invention generally relates to an article transferring food modifiers to foods in contact therewith. The article comprises a coating supported on a support member, wherein the coating comprises a carrier material containing lipid which releasably retains a food modifier. The article provides for heat-activated transfer or water-activated transfer of a food modifier from the coating to food materials in contact therewith.

    摘要翻译： 本发明一般涉及将食品改性剂转移到与其接触的食品的物品。 所述制品包含支撑在支撑构件上的涂层，其中所述涂层包含含可释放地保留食品改性剂的含脂质的载体材料。 该制品提供了食品改性剂从涂层到与其接触的食品材料的热激活转移或水激活转移。