公开(公告)号：EP3023411B1

公开(公告)日：2018-12-05

申请号：EP14825779.3

申请日：2014-07-03

Applicant: Kumiai Chemical Industry Co., Ltd.

Inventor： TANI, Shinki ,  KOGA, Minekazu ,  MATSUMOTO, Izumi

IPC: C07C67/313 ,  C07C67/31 ,  C07C69/675 ,  C07C69/716

CPC classification number: C07C67/313 ,  C07C67/31 ,  C07C69/716 ,  C07C69/675

Abstract: Provided is a method for producing an industrially useful ketomalonic acid compound such as ketomalonic acid diesters, or a hydrate thereof, by a method more favorable from an economic and environmental standpoint and from a safety standpoint. The present invention relates to a method involving reacting a malonic acid compound represented by general formula (1) (in the formula, The each Rs indicate an alkyl group, a cycloalkyl group, etc.) with chlorine dioxide to produce a ketomalonic acid compound represented by the general formula (2) (in the formula, R has the same meaning as above), or a hydrate thereof.

公开(公告)号：EP4053125A2

公开(公告)日：2022-09-07

申请号：EP20835297.1

申请日：2020-10-30

Applicant: Kumiai Chemical Industry Co., Ltd.

Inventor： UCHIDA, Yukio ,  ATSUMI, Naoya ,  TANI, Shinki ,  OKADA, Koji ,  MURAI, Yuta ,  CAOIMHIN, Arnott

IPC: C07D413/12 ,  C07B61/00

Abstract: The present invention provides a sulfone derivative that is useful as a herbicide, and an industrially preferable production method for an intermediate of said derivative. Provided is a production method for a compound of formula (4), the method including step ii, wherein step ii is a step for producing a compound of formula (4) by reacting a compound of formula (2) with a compound of formula (3) in the presence of a base. Also provided is a production method for a compound of formula (5), the method including step iii, wherein step iii is a step for producing a compound of formula (5) by reacting a compound of formula (4) with hydrogen peroxide in the presence of a metal catalyst.

公开(公告)号：EP3109227B1

公开(公告)日：2020-04-08

申请号：EP15748585.5

申请日：2015-02-06

Applicant: Kumiai Chemical Industry Co., Ltd.

Inventor： TANI, Shinki

IPC: C07C67/313 ,  C07C67/31 ,  C07C69/675 ,  C07C69/716 ,  C07B61/00

公开(公告)号：EP2754651B1

公开(公告)日：2017-12-06

申请号：EP12807434.1

申请日：2012-07-04

Applicant: Kumiai Chemical Industry Co., Ltd.

Inventor： TANI, Shinki ,  YADOMATSU, Nami ,  IKUMI, Akiko ,  HIRANO, Yuuki ,  IDO, Takuya

IPC: C07C201/06 ,  C07B61/00 ,  C07C205/06 ,  C07C227/08 ,  C07C229/56

CPC classification number: C07C201/06 ,  C07C205/06 ,  C07C205/58

Abstract: There is provided a method for producing a nitrobenzene compound that can be implemented by a simple operation under mild conditions without using a special reaction apparatus. [Solution] The present invention provides a method for producing a nitrobenzene compound represented by general formula (2), wherein R 1 and R 5 are the same or different, and each is a halogen atom or another functional group, and R 2 , R 3 , and R 4 are the same or different, and each is a hydrogen atom or another functional group, comprising oxidizing an aniline compound represented by general formula (1), wherein R 1 , R 2 , R 3 , R 4 , and R 5 are the same as described above, with hydrogen peroxide in the presence of a tungsten compound under an acidic condition, followed by oxidation with hydrogen peroxide under a neutral to alkaline condition.