公开(公告)号：EP1446015A4

公开(公告)日：2005-11-23

申请号：EP02801789

申请日：2002-10-18

申请人： LIFECELL CORP ,  WRIGHT MEDICAL TECH INC

发明人： LIVESEY STEPHEN A ,  MCQUILLAN DAVID J ,  BENIKER HERBERT DANIEL ,  BOERBOOM LAWRENCE E ,  HAGGARD WARREN O

IPC分类号： A61L27/00 ,  A61K35/12 ,  A61K35/22 ,  A61K35/32 ,  A61K35/34 ,  A61K35/36 ,  A61K35/38 ,  A61K35/44 ,  A61K35/55 ,  A61K45/00 ,  A61P1/00 ,  A61P9/00 ,  A61P9/04 ,  A61P13/02 ,  A61P13/10 ,  A61P17/00 ,  A61P19/02 ,  A61P19/08 ,  A61P21/00 ,  A61P25/00 ,  A61P43/00 ,  A01N63/00 ,  A61K48/00

CPC分类号： A61K35/32 ,  A61K35/36 ,  A61K38/00 ,  A61L27/3608 ,  A61L27/362 ,  A61L27/3804 ,  A61L27/54 ,  A61L2430/02

摘要： The invention provides methods of repairing damage to, or defects in, mammalian tissues or organs. In these methods, a particulate or non-particulate acellular matrix made from a tissue or organ other than the tissue or organ being repaired is placed in or on the organ or tissue that is being repaired.

公开(公告)号：EP1651050A4

公开(公告)日：2009-08-05

申请号：EP04779040

申请日：2004-07-21

申请人： LIFECELL CORP

发明人： MCQUILLAN DAVID J ,  GRIFFEY EDWARD S ,  BENIKER HERBERT DANIEL ,  XU HUI

IPC分类号： A01N63/00 ,  A01K67/027 ,  A01K67/033 ,  A61F2/02 ,  A61K48/00

CPC分类号： A61K35/32 ,  A61F2/0063 ,  A61K35/36 ,  A61K38/17 ,  A61K45/06 ,  A61L27/3604 ,  A61L27/3683 ,  A61L27/3695 ,  A61L2430/40 ,  C07K16/18 ,  C12N2533/92 ,  G01N33/6854 ,  A61K2300/00

摘要： The invention provides acellular tissue matrices made from collagen containing tissues of animals genetically modified so as to be deficient in the galactose 1,3-galactose epitope and methods of making and using such acellular tissue matrices.

公开(公告)号：EP1809735A4

公开(公告)日：2007-11-07

申请号：EP05808684

申请日：2005-10-06

申请人： LIFECELL CORP

发明人： SUN WENDELL ,  BENIKER HERBERT DANIEL ,  MCQUILLAN DAVID J

IPC分类号： A01N1/02 ,  A61K35/12 ,  C12N5/071

CPC分类号： C12N5/0697 ,  A01N1/00 ,  A01N1/02 ,  A01N1/0221 ,  A01N1/0231 ,  A01N1/0294 ,  A61L27/3633 ,  A61L27/3683 ,  A61L27/3691 ,  A61L27/60 ,  A61L2430/40

摘要： The invention provides methods of storing acellular tissue matrices in which a substantial portion of water in the matrices is replaced with a water-replacing agent, e.g., glycerol. Also included in the invention are compositions made by these methods as well as methods of treatment using such compositions.