公开(公告)号：EP0800519B1

公开(公告)日：2003-10-22

申请号：EP95944089.2

申请日：1995-12-13

申请人： LIGAND PHARMACEUTICALS, INC.

发明人： JONES, Todd, K. c/o Ligand Pharmaceuticals,Inc. ,  GOLDMAN, Mark, E. ,  POOLEY, Charlotte, L., F. ,  WINN, David, T. ,  EDWARDS, James, E. ,  WEST, Sarah, J. ,  TEGLEY, Christopher, M. c/o Ligand ,  ZHI, Lin ,  HAMANN, Lawrence, G. ,  FARMER, Luc, J. ,  DAVIS, Robert, J.

IPC分类号： C07D215/06 ,  A61K31/47 ,  C07D417/04 ,  C07D413/04 ,  C07D401/04 ,  C07D221/18 ,  C07D493/04 ,  C07D471/04

CPC分类号： C07D401/04 ,  C07D215/06 ,  C07D221/18 ,  C07D311/80 ,  C07D413/04 ,  C07D417/04 ,  C07D471/04 ,  C07D491/04

公开(公告)号：EP0800519A1

公开(公告)日：1997-10-15

申请号：EP95944089.0

申请日：1995-12-13

申请人： LIGAND PHARMACEUTICALS, INC.

发明人： JONES, Todd, K. ,  GOLDMAN, Mark, E. ,  POOLEY, Charlotte, L., F. ,  WINN, David, T. ,  EDWARDS, James, E. ,  WEST, Sarah, J. ,  TEGLEY, Christopher, M. ,  ZHI, Lin ,  HAMANN, Lawrence, G. ,  FARMER, Luc, J. ,  DAVIS, Robert, J.

IPC分类号： A61K31 ,  A61P5 ,  C07D215 ,  C07D221 ,  C07D311 ,  C07D401 ,  C07D405 ,  C07D409 ,  C07D413 ,  C07D417 ,  C07D471 ,  C07D491 ,  C07D493 ,  C07D495

CPC分类号： C07D401/04 ,  C07D215/06 ,  C07D221/18 ,  C07D311/80 ,  C07D413/04 ,  C07D417/04 ,  C07D471/04 ,  C07D491/04

摘要： Non-steroidal compounds which are high affinity, high selectivity modulators for steroid receptors are disclosed. Also disclosed are pharmaceutical compositions incorporating such compounds, methods for employing the disclosed compounds and compositions for treating patients requiring steroid receptor agonist or antagonist therapy, intermediates useful in the preparation of the compounds and processes for the preparation of the steroid receptor modulator compounds.