公开(公告)号：EP3028719A1

公开(公告)日：2016-06-08

申请号：EP14195663.1

申请日：2014-12-01

申请人： Lanxess Inc. ,  The University of Western Ontario

发明人： Gilles, Elizabeth R. ,  McEachran, Matthew ,  Trant, John Frederick ,  Sran, Inderpreet ,  Ferrari, Lorenzo

IPC分类号： A61K47/48 ,  A61L31/10 ,  A61L31/16

CPC分类号： A61L31/10 ,  A61F2/90 ,  A61F2210/0076 ,  A61F2250/0067 ,  A61K47/48176 ,  A61K47/48992 ,  A61K47/58 ,  A61K47/6957 ,  A61L31/16

摘要： A polymer-drug conjugate, which can be used in medical applications such as stents, has at least one active agent conjugated through a carboxylic acid moiety to a copolymer derived from at least one isoolefin monomer and at least one copolymerizable monomer, where the copolymerizable monomer is at least one multiolefin monomer, a β-pinene monomer or a mixture thereof. Such conjugates show improved adhesion to stainless steel and a substantial decrease in burst release of paclitaxel form a drug eluting stent (DES).

摘要翻译： 可用于医疗应用如支架的聚合物 - 药物缀合物具有至少一种通过羧酸部分缀合至由至少一种异烯烃单体和至少一种可共聚单体衍生的共聚物的活性剂，其中可共聚单体 是至少一种多烯烃单体，β-蒎烯单体或其混合物。 这种缀合物显示出对不锈钢的改善的粘附性，并且紫杉醇的爆发释放显着降低形成药物洗脱支架（DES）。

公开(公告)号：EP1512716B1

公开(公告)日：2009-11-04

申请号：EP04019114.0

申请日：2004-08-12

申请人： Lanxess Inc.

发明人： Pazur, Richard ,  Ferrari, Lorenzo

IPC分类号： C08K3/00 ,  C08L13/00 ,  C08L15/00

CPC分类号： C08L15/005 ,  C08K3/013 ,  C08K3/08 ,  C08K3/22 ,  C08K2201/01 ,  C08L13/00 ,  C08L2666/08

摘要： The present invention relates to a rubber compound comprising at least one hydrogenated carboxylated nitrile rubber, at least one hydrogenated nitrile rubber and at least one magnetic compound, a curable rubber compound comprising said rubber compound and at least one vulcanization agent and a magnetic shaped article comprising said rubber compound.

公开(公告)号：EP3178889A1

公开(公告)日：2017-06-14

申请号：EP15199556.0

申请日：2015-12-11

申请人： Lanxess Inc. ,  University of Western Ontario

发明人： Ferrari, Lorenzo ,  Adkinson, Dana ,  Jun, Yang ,  Yu, Binyu ,  Pally, Maxim ,  Kobe, Brad

IPC分类号： C09D5/00

CPC分类号： C09D5/24 ,  C08K3/041 ,  C09D5/1681 ,  C09D7/68 ,  C09D7/69 ,  C09D7/70

摘要： A polymer nanocomposite coating of an elastomeric film containing at least 30 wt% conductive nanoparticles based on combined weight of elastomer and conductive nanoparticles is provided. The conductive nanoparticles have an average particle size along each dimension of less than 500 nm for nanoparticles having an aspect ratio of less than 20:1 or have an average particle size along each dimension of less than 2000 nm for nanoparticles having an aspect ratio of 20:1 or greater. The conductive nanoparticles are formed into hierarchical micro- and nano-sized aggregates having re-entrant morphology. The coating is both superoleophobic and conductive and retains these properties even when stretched under strain to over 100%. The coatings may be produced with simple spray technology.

摘要翻译： 提供了基于弹性体和导电纳米颗粒的组合重量的包含至少30重量％的导电纳米颗粒的弹性体薄膜的聚合物纳米复合涂层。 对于纵横比小于20:1的纳米颗粒，导电纳米颗粒沿每个尺寸的平均颗粒尺寸小于500nm，或者对于纵横比为20的纳米颗粒，沿每个尺寸的平均颗粒尺寸小于2000nm ：1或更大。 导电纳米粒子形成具有凹入形态的分级微米和纳米尺寸的聚集体。 该涂层既具有超疏油性又具有导电性，并且即使在应变下拉伸超过100％时也能保持这些性能。 涂层可以用简单的喷涂技术生产。