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公开(公告)号：EP3504291B1
公开(公告)日：2020-10-28
申请号：EP17765293.0
申请日：2017-08-24
发明人： YORK, Adam , WELCH, Eric , GEE, Kyle , WANG, Xin , AGGELER, Robert , HU, Yi-Zhen
IPC分类号： C09K11/02 , C09K11/06 , C08G61/10 , C08G61/12 , G01N33/533
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公开(公告)号：EP3472210A1
公开(公告)日：2019-04-24
申请号：EP17735277.0
申请日：2017-06-16
发明人： AGNEW, Brian , AGGELER, Robert , BRAWER, Rolando
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公开(公告)号：EP3504291A1
公开(公告)日：2019-07-03
申请号：EP17765293.0
申请日：2017-08-24
发明人： YORK, Adam , WELCH, Eric , GEE, Kyle , WANG, Xin , AGGELER, Robert , HU, Yi-Zhen
IPC分类号： C09K11/02 , C09K11/06 , C08G61/10 , C08G61/12 , G01N33/533
摘要： Water-soluble, fluorescent particles and compositions, kits, and methods of making and using such particles are disclosed. Processes for preparing fluorescent particles and for controlling the size, polydispersity and optical properties of such particles also are provided.
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公开(公告)号：EP3507603A1
公开(公告)日：2019-07-10
申请号：EP17765041.3
申请日：2017-09-01
发明人： DESAI, Surbhi , NLEND, Marie , GEE, Kyle , BAKER, Matthew , AGGELER, Robert , SWEENEY, Scott , RUKAVISHNIKOV, Aleksey , HUANG, Shih-Jung
IPC分类号： G01N33/58 , G01N33/533
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5.发明公开DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE 审中-公开二苯并噻唑单体和聚合物及其制备和使用方法
公开(公告)号：EP3215515A1
公开(公告)日：2017-09-13
申请号：EP15762807.4
申请日：2015-08-14
发明人： GEE, Kyle , WANG, Xin , KANG, Hee, Chol , CHEN, Aimei , WU, Yexin , HU, Yi-Zhen , AGGELER, Robert , LOW, Quentin
IPC分类号： C07F7/08 , C08G61/12 , C08L65/00 , G01N33/533 , G01N33/58
CPC分类号： C08G61/123 , C07F7/0816 , C07F7/083 , C08G2261/122 , C08G2261/124 , C08G2261/1424 , C08G2261/145 , C08G2261/1644 , C08G2261/1646 , C08G2261/3142 , C08G2261/3244 , C08G2261/334 , C08G2261/344 , C08G2261/411 , C08G2261/522 , C08G2261/5222 , C08G2261/72 , C08G2261/94 , C08L65/00 , C09K11/06 , C09K2211/1416 , C09K2211/1491 , G01N33/533 , G01N33/545 , G01N33/582 , H01L51/0039 , H01L51/0043 , H01L51/0094
摘要： Water-soluble, conjugated polymers containing one or more dibenzosilole monomer residues, as well as compositions, kits, and methods of making and using such polymers are disclosed. Also disclosed are dibenzosilole derivatives substituted with one or more water-solubilizing groups, and methods of making and using such derivatives to prepare water-soluble dibenzosilole polymers.
摘要翻译： 公开了含有一种或多种二苯并噻咯单体残基的水溶性共轭聚合物，以及制备和使用这种聚合物的组合物，试剂盒和方法。 还公开了用一个或多个水溶性基团取代的二苯并硅氧烷衍生物，以及制备和使用这些衍生物制备水溶性二苯并硅氧烷聚合物的方法。
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6.发明公开METHODS AND COMPOSITIONS FOR ENZYME-MEDIATED SITE-SPECIFIC RADIOLABELING OF GLYCOPROTEINS 审中-公开方法和组合物的放射性糖蛋白的酶介导的组特定的贴标
公开(公告)号：EP2912459A2
公开(公告)日：2015-09-02
申请号：EP13786595.2
申请日：2013-10-25
发明人： AGNEW, Brian , AGGELER, Robert , KANG, Hee Chol , CHEN, Aimei , GEE, Kyle
IPC分类号： G01N33/50
CPC分类号： A61K51/10 , C07K14/435 , C07K16/18 , C12P21/005 , C12P21/06 , G01N33/534 , G01N33/582 , G01N33/6854
摘要： Provided herein are methods, compositions and kits for use in the site-specific labeling of glycoproteins comprising a combination of enzyme-mediated incorporation of modified sugars comprising a chemical handle and cycloaddition chemistry with a labeling molecule comprising a reactive group, a metal ion chelator, and/or a fluorophore.
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