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11 条记录 (耗时 0.02 秒)

    Amniotic fluid derived cells
    1.
    发明公开
    Amniotic fluid derived cells 有权
    从羊水细胞

    公开(公告)号：EP1780267A2

    公开(公告)日：2007-05-02

    申请号：EP06252751.0

    申请日：2006-05-26

    申请人： LifeScan, Inc.

    发明人： Rezania, Alireza ,  Xu, Jean

    IPC分类号： C12N5/08

    CPC分类号： C12N5/0605 ,  C12N2500/02 ,  C12N2533/52 ,  C12N2533/54

    摘要： This invention relates to an expandable population of amniotic fluid-derived cells that can be differentiated into a β-cell lineage. This invention also provides methods for isolating and expanding such amniotic fluid-derived cells, as well as related methods and compositions for utilizing such cells in the therapeutic treatment of diabetes.

    Compositons and methods to create a vascularized environment for cellular transplantation
    5.
    发明公开
    Compositons and methods to create a vascularized environment for cellular transplantation 审中-公开
    组合物和方法用于制备血管环境对细胞移植

    公开(公告)号：EP1797909A3

    公开(公告)日：2007-09-05

    申请号：EP06256045.3

    申请日：2006-11-27

    申请人： LifeScan, Inc.

    发明人： Xu, Jean ,  Harris, Ian R.

    IPC分类号： A61L27/38 ,  A61L27/54

    CPC分类号： A61L27/38 ,  A61L27/54 ,  A61L2300/252 ,  A61L2300/402 ,  A61L2300/41 ,  A61L2300/414 ,  A61L2300/604 ,  A61L2300/64

    摘要： The present invention generally relates to biocompatible devices suitable for promoting the movement of cells from a first location to a second location and their retention in the second location. In particular, the present invention relates to an implant, comprising a biocompatible support loaded with at least one pharmaceutical agent capable promoting the movement of cells from a first location to a second location and their retention in the second location. The at least one pharmaceutical agent promotes vascularization at or near the implant site. Vascularization of the implanted support results in enhanced survival of cells optionally incorporated within the support. Methods for treating a disease or injury via implanting the support of the present invention are also provided.

    Amniotic fluid derived cells
    7.
    发明公开
    Amniotic fluid derived cells 审中-公开
    羊水衍生细胞

    公开(公告)号：EP2302036A3

    公开(公告)日：2011-06-15

    申请号：EP10184689.7

    申请日：2006-05-26

    申请人： Lifescan, Inc.

    发明人： Rezania, Alireza ,  Xu, Jean

    IPC分类号： C12N5/073

    CPC分类号： C12N5/0605 ,  C12N2500/02 ,  C12N2533/52 ,  C12N2533/54

    摘要： This invention relates to an expandable population of amniotic fluid-derived cells that can be differentiated into a β-cell lineage. This invention also provides methods for isolating and expanding such amniotic fluid-derived cells, as well as related methods and compositions for utilizing such cells in the therapeutic treatment of diabetes.

    摘要翻译： 本发明涉及可分化为β细胞谱系的可扩增羊水来源细胞群。 本发明还提供了用于分离和扩增这种羊水来源的细胞的方法，以及用于在糖尿病的治疗中利用这些细胞的相关方法和组合物。

    Amniotic fluid derived cells
    8.
    发明公开
    Amniotic fluid derived cells 审中-公开
    Zellen aus Fruchtwasser

    公开(公告)号：EP2302036A2

    公开(公告)日：2011-03-30

    申请号：EP10184689.7

    申请日：2006-05-26

    申请人： Lifescan, Inc.

    发明人： Rezania, Alireza ,  Xu, Jean

    IPC分类号： C12N5/073

    CPC分类号： C12N5/0605 ,  C12N2500/02 ,  C12N2533/52 ,  C12N2533/54

    摘要： This invention relates to an expandable population of amniotic fluid-derived cells that can be differentiated into a β-cell lineage. This invention also provides methods for isolating and expanding such amniotic fluid-derived cells, as well as related methods and compositions for utilizing such cells in the therapeutic treatment of diabetes.

    摘要翻译： 本发明涉及可分化为二细胞谱系的羊水来源细胞的可扩展群体。 本发明还提供了用于分离和扩增这种羊水来源的细胞的方法，以及用于在糖尿病的治疗性治疗中利用这种细胞的相关方法和组合物。

    Amniotic fluid derived cells
    9.
    发明公开
    Amniotic fluid derived cells 有权

    公开(公告)号：EP1780267A3

    公开(公告)日：2007-08-01

    申请号：EP06252751.0

    申请日：2006-05-26

    申请人： LifeScan, Inc.

    发明人： Rezania, Alireza ,  Xu, Jean

    IPC分类号： C12N5/08

    CPC分类号： C12N5/0605 ,  C12N2500/02 ,  C12N2533/52 ,  C12N2533/54

    摘要： This invention relates to an expandable population of amniotic fluid-derived cells that can be differentiated into a β-cell lineage. This invention also provides methods for isolating and expanding such amniotic fluid-derived cells, as well as related methods and compositions for utilizing such cells in the therapeutic treatment of diabetes.

    Compositons and methods to create a vascularized environment for cellular transplantation
    10.
    发明公开
    Compositons and methods to create a vascularized environment for cellular transplantation 审中-公开
    组合物和方法用于制备血管环境对细胞移植

    公开(公告)号：EP1797909A2

    公开(公告)日：2007-06-20

    申请号：EP06256045.3

    申请日：2006-11-27

    申请人： LifeScan, Inc.

    发明人： Xu, Jean ,  Harris, Ian R.

    IPC分类号： A61L27/38 ,  A61L27/54

    CPC分类号： A61L27/38 ,  A61L27/54 ,  A61L2300/252 ,  A61L2300/402 ,  A61L2300/41 ,  A61L2300/414 ,  A61L2300/604 ,  A61L2300/64

    摘要： The present invention generally relates to biocompatible devices suitable for promoting the movement of cells from a first location to a second location and their retention in the second location. In particular, the present invention relates to an implant, comprising a biocompatible support loaded with at least one pharmaceutical agent capable promoting the movement of cells from a first location to a second location and their retention in the second location. The at least one pharmaceutical agent promotes vascularization at or near the implant site. Vascularization of the implanted support results in enhanced survival of cells optionally incorporated within the support. Methods for treating a disease or injury via implanting the support of the present invention are also provided.

    摘要翻译： 本发明基因的反弹涉及适用于电视节目预告婷生物相容性装置细胞从第一位置移动到第二位置及其在所述第二位置保持。 特别地，本发明涉及一种在植入物，包括负载有至少一种药物活性剂能够宣传片婷细胞的运动从第一位置到第二位置及其在所述第二位置保持生物相容性支持。 至少一个药剂在植入部位或其附近的血管促进。 在细胞的存活增强植入支撑结果的血管形成在载体内可选地并入。 因此，提供用于通过植入本发明的支撑治疗疾病或损伤的方法。