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1.发明公开Implantable pouch seeded with insulin-producing cells to treat diabetes 审中-公开植入袋besiedlet与产生胰岛素的细胞治疗糖尿病
公开(公告)号：EP1466632A1
公开(公告)日：2004-10-13
申请号：EP04252017.1
申请日：2004-04-02
申请人： Lifescan, Inc.
摘要： An implantable pouch and methods for implanting cells or cellular matter in mammals, comprising reinforced porous foam and a lumen. The lumen contains an insert that may or may not be removed prior to transplantation. The lumen may be loaded with at least one cell type expressing at least one transcription factor characteristic of a mammalian pancreatic beta cell.
摘要翻译： 用于植入的细胞或细胞物质在哺乳动物中可植入的袋和方法，其包括增强的多孔泡沫和内腔。 卷中包含插入件确实可以或可以不被移植前除去。 内腔可以与至少一种细胞类型表达的哺乳动物的胰腺β细胞中的至少一个转录因子特性被下载。
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公开(公告)号：EP1466633A1
公开(公告)日：2004-10-13
申请号：EP04252019.7
申请日：2004-04-02
申请人： Lifescan, Inc.
发明人： Rezania, Alireza , Zimmerman, Mark
CPC分类号： A61L27/3852 , A61L27/3847 , A61L27/48 , A61L27/56 , C08L67/04
摘要： Implantable, biocompatible scaffolds containing a biocompatible, porous, polymeric matrix, a biocompatible, porous, fibrous mat encapsulated by and disposed within said polymeric matrix, and a plurality of mammalian cells seeded within said tissue scaffold. The invention also is directed to methods of treating disease or structural defects in a mammal utilizing the scaffolds of the invention.
摘要翻译： 包含生物相容性多孔聚合物基质的可植入生物相容性支架，被所述聚合物基质包封和设置在所述聚合物基质内的生物相容性多孔纤维垫以及接种在所述组织支架内的多个哺乳动物细胞。 本发明还涉及利用本发明的支架治疗哺乳动物的疾病或结构缺陷的方法。
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