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公开(公告)号：EP1108212A1
公开(公告)日：2001-06-20
申请号：EP99943950.8
申请日：1999-08-27
IPC分类号： G01N33/53 , G01N33/567
CPC分类号： G01N33/5091 , G01N33/6893 , G01N2800/324
摘要： The invention provides methods and materials for diagnosing an angina condition in a patient. Specifically, the invention provides methods and materials for classifying an angina condition as either stable or unstable. In addition, the invention provides methods and materials for determining an individual's predisposition to have a stable or unstable angina condition. The invention also provides kits for classifying an angina condition as either stable or unstable as well as kits for determining an individual's predisposition to have a stable or unstable angina condition.
摘要翻译： 本发明提供了用于诊断患者的心绞痛状况的方法和材料。 具体而言，本发明提供了用于将心绞痛病症分类为稳定或不稳定的方法和材料。 此外，本发明提供了用于确定个体倾向于具有稳定或不稳定的心绞痛症状的方法和材料。 本发明还提供用于将心绞痛病症分类为稳定或不稳定的试剂盒以及用于确定个体具有稳定或不稳定心绞痛病症的试剂盒的试剂盒。
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公开(公告)号：EP1066047A1
公开(公告)日：2001-01-10
申请号：EP99914140.1
申请日：1999-03-25
CPC分类号： A61K38/162 , A61K31/70 , A61K38/1841 , A61K38/2026 , A61K38/2066 , A61K38/2086 , A61K48/00 , Y10S514/825 , Y10S514/886 , A61K2300/00
摘要： The invention provides methods and materials related to the treatment of inflammatory diseases such as rheumatoid arthritis. Specifically, the invention provides methods and materials for treating inflammation by reducing production of an inflammatory cytokine such as IFN-η, IL-1β, and TNF-α. The invention also provides methods and materials for identifying reagents that can be used to treat inflammatory diseases. Specifically, the invention provides non-human animals containing human synovial tissue as well as methods for using such non-human animals to determine the influence of various test reagents on the inflamed state of human synovial tissue.
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