公开(公告)号：EP0759310A2

公开(公告)日：1997-02-26

申请号：EP96305643.7

申请日：1996-07-31

申请人： MEDTRONIC, INC.

发明人： Francischelli, David

IPC分类号： A61N1/36 ,  A61N1/39

CPC分类号： A61N1/3962 ,  A61N1/36042 ,  A61N1/3621

摘要： A cardiac assist device which provides an improved method of conditioning a skeletal muscle graft 3. In particular the present invention features a memory 526. The memory contains a regime to transform the muscle. Typically the regime has a schedule of various muscle stimulation parameters which may be varied during the muscle training period. When the memory is activated the muscle conditioning regime is automatically altered during the desired time period. In the preferred embodiment the memory features several training schedules, any one of which may be selected. The present invention further features an interrupt to temporarily disable the muscle training regime in the event the onset of a cardiac arrythmia is detected. Once the arrythmia is confirmed, then the cardiac assist device delivers therapeutic stimulation to the heart 2. After the termination of the arrythmia is confirmed the muscle training regime is re-initiated at the point in the therapy it would have been if it had not been inhibited.

摘要翻译： 一种心脏辅助装置，其提供改善骨骼肌移植物3的调节方法。特别地，本发明的特征在于存储器526.存储器包含转化肌肉的状态。 通常，该制度具有各种肌肉刺激参数的时间表，其可以在肌肉训练期间变化。 当记忆被激活时，肌肉调理状态在期望的时间段内自动改变。 在优选实施例中，存储器具有若干训练计划，其中任何一个可被选择。 本发明还具有在检测到心脏性心律失常的发作的情况下临时禁用肌肉训练状态的中断。 一旦证实了心律失常，那么心脏辅助装置向心脏2递送治疗刺激。确认了心律失常的终止之后，肌肉训练方案在治疗的时候重新开始，如果没有 抑制。

公开(公告)号：EP0759312A2

公开(公告)日：1997-02-26

申请号：EP96305736.9

申请日：1996-08-02

申请人： MEDTRONIC, INC.

发明人： Francischelli, David ,  Hammargren, John ,  Neisz, Johann J. ,  Peterson, David K. ,  Weijand, Koen J.

IPC分类号： A61N1/36 ,  A61N1/39

CPC分类号： A61N1/3621 ,  A61N1/36042 ,  A61N1/3962

摘要： A cardiac assist device having muscle augmentation after a confirmed arrhythmia. In particular the present invention operates, in a first embodiment, to sense a cardiac event, next it determines whether the cardiac event is a cardiac arrhythmia, if the event is not a cardiac arrhythmia the devices delivers stimulation to a skeletal muscle grafted about a heart, but if the event is a cardiac arrhythmia the device inhibits delivery of skeletal muscle stimulation and once the arrhythmia is confirmed, then delivers therapeutic stimulation to the heart. In a second embodiment the present invention operates to re-initiate skeletal muscle stimulation once the arrhythmia is confirmed but prior to the delivery of the therapeutic stimulation to the heart.

摘要翻译： 一种心脏辅助装置，在证实心律失常后具有肌肉增强功能。 具体地，本发明在第一实施例中用于感测心脏事件，接下来确定心脏事件是否为心律失常，如果事件不是心律失常，那么设备将刺激递送到围绕心脏移植的骨骼肌 ，但如果该事件是心律失常，则该装置抑制骨骼肌刺激的传递，并且一旦证实了心律失常，则将治疗刺激传递给心脏。 在第二实施例中，一旦证实心律失常，但在将治疗刺激递送至心脏之前，本发明用于重新启动骨骼肌肉刺激。

公开(公告)号：EP0759309A2

公开(公告)日：1997-02-26

申请号：EP96305588.4

申请日：1996-07-30

申请人： MEDTRONIC, INC.

发明人： Francischelli, David ,  Gealow, Kendra K. ,  Grandjean, Pierre A. ,  Hammargren, John ,  Neisz, Johann J. ,  Peterson, David K.

IPC分类号： A61N1/36 ,  A61N1/39

CPC分类号： A61N1/3621 ,  A61N1/36042 ,  A61N1/3962

摘要： A device and algorithm for a combined cardiomyostimulator and a cardiac pacer-cardioverter-defibrillator. In particular the present invention operates, in a first embodiment, to deliver stimulation to a skeletal muscle 3 grafted about a heart 2; sense depolarizations of a patient's heart; measure the intervals separating successive depolarizations of the patient's heart; define first and second interval ranges; determine the number of the measured intervals falling within the first and second interval ranges; inhibit the delivery of stimulation to a skeletal muscle grafted about a heart upon the sensing of a depolarization within the first or second interval range; detect the occurrence of a first type of arrhythmia when the number of the measured intervals falling within the first interval range equals a first predetermined value; detect the occurrence of a second type of an arrhythmia when the number of the intervals falling within the second interval range equals a second predetermined value; deliver a first type of arrhythmia therapy in response to the detection of the first arrhythmia; and deliver a second type of arrhythmia therapy in response to the detection of the second arrhythmia, the second type of arrhythmia therapy having a cardiac stimulation component and a skeletal muscle component.

摘要翻译： 的装置和算法用于组合cardiomyostimulator和心脏起搏器-心律转复除颤器。 特别是在本发明工作在第一实施方式中，递送刺激到接枝约一个心脏3 2骨骼肌; 患者的心脏感去极化; 测量间隔分离患者心脏的去极化连续; 限定第一和第二间隔的范围; 确定性矿井间隔测量落在第一和第二间隔的范围内的数目; 抑制到接枝大约在所述第一或第二时间间隔范围内的去极化的感测心脏的骨骼肌递送刺激; 检测第一类型的心律失常当测得的时间间隔落在第一间隔范围内的数目等于第一预定值的的发生; 检测的第二类型的心律不齐。当间隔落在第二间隔范围内的数目等于第二预定值的发生; 响应于检测到第一心律失常的输送第一类型的心律失常治疗; 以及响应提供一个第二类型的心律不齐的治疗，以检测所述第二心律失常，具有心脏刺激组分和骨骼肌组分的第二类型的心律失常治疗。