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1.HUMAN HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CATION CHANNEL HCN3 审中-公开
标题翻译: 曼彻斯特超高效液相色谱仪,德克尔循环系列润滑油GESTEUERTER KATIONENKANAL HCN3公开(公告)号:EP1358196A4
公开(公告)日:2004-11-03
申请号:EP01991006
申请日:2001-12-14
申请人: MERCK & CO INC
CPC分类号: C07K14/705
摘要: The present invention is directed to novel human DNA sequences encoding human HCN3 proteins, the protein encoded by the DNA sequences, vectors comprising the DNA sequences, host cells containing the vectors, and methods of identifying inhibitors and activators of cation channels containing the human HCN3 proteins.
摘要翻译: 本发明涉及编码人HCN3蛋白质的新型人DNA序列,由DNA序列编码的蛋白质,包含DNA序列的载体,含有载体的宿主细胞以及鉴定含有人HCN3蛋白质的阳离子通道的抑制剂和激活剂的方法 。
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公开(公告)号:EP1395602A4
公开(公告)日:2004-05-06
申请号:EP01989886
申请日:2001-11-02
申请人: MERCK & CO INC
IPC分类号: G01N21/64 , A61K38/00 , A61K45/00 , A61P1/00 , A61P25/00 , A61P25/02 , A61P25/04 , A61P25/18 , A61P25/22 , A61P43/00 , C07K14/47 , C07K14/705 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12Q1/02 , C12Q1/68 , G01N21/78 , G01N27/416 , G01N33/15 , G01N33/50 , G01N33/53 , G01N33/566 , C07H21/02
CPC分类号: C07K14/705 , A61K38/00
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3.HUMAN HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CATION CHANNEL HCN1 审中-公开
标题翻译: MENSCHLICHER高分子化合物,DURCH ZYKLISCHES NUKLEOTID GESTEUERTER KATIONENKANAL HCN1公开(公告)号:EP1407011A4
公开(公告)日:2004-07-21
申请号:EP02720890
申请日:2002-01-18
申请人: MERCK & CO INC
发明人: FOLANDER KIMBERLY L , LIU YUAN , SWANSON RICHARD J
IPC分类号: C07K14/705 , C12N15/12 , C12N15/00
CPC分类号: C07K14/705
摘要: The present invention is directed to novel human DNA sequences encoding human HCN1 proteins, the protein encoded by the DNA sequences, vectors comprising the DNA sequences, host cells containing the vectors, and methods of identifying inhibitors and activators of cation channels containing the human HCN1 proteins.
摘要翻译: 本发明涉及编码人HCN1蛋白质的新型人DNA序列,由DNA序列编码的蛋白质,包含DNA序列的载体,含有载体的宿主细胞,以及鉴定含有人HCN1蛋白质的阳离子通道的抑制剂和激活剂的方法 。
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">4.DNA ENCODING THE BETA SUBUNIT OF A MAMMALIAN "MAXI-K" POTASSIUM CHANNEL 失效
标题翻译: 对于“MAXI-K”哺乳动物DNA编码CALZIUMKANALSβ亚基公开(公告)号:EP0759983A4
公开(公告)日:1997-07-16
申请号:EP95919767
申请日:1995-05-09
申请人: MERCK & CO INC
发明人: KACZOROWSKI GREGORY J , GARCIA MARIA L , LEONARD REID J , MCMANUS OWEN B , SWANSON RICHARD J , FOLANDER KIMBERLY LEE
IPC分类号: C12N15/09 , A61K38/00 , A61P9/00 , A61P9/08 , A61P9/10 , A61P13/02 , A61P15/00 , A61P21/02 , A61P25/04 , A61P29/00 , C07H21/04 , C07K14/47 , C07K14/705 , C07K16/18 , C12N1/19 , C12N5/10 , C12N15/12 , C12P21/02 , C12R1/865 , C12R1/91 , A61K38/18 , A61K39/395 , A61K48/00 , C07K16/28 , C12N1/21 , C12N15/63
CPC分类号: C07K14/705 , A61K38/00 , C12N2799/026
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公开(公告)号:EP1224265A4
公开(公告)日:2004-11-24
申请号:EP00968933
申请日:2000-10-10
申请人: MERCK & CO INC
发明人: SWANSON RICHARD J , LIU YUAN , FOLANDER KIMBERLY
IPC分类号: G01N33/50 , C07K14/47 , C07K14/705 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/566 , G01N33/68 , C07K14/71 , C12N15/63 , C12N15/64 , G01N33/53 , G01N33/567
CPC分类号: G01N33/6872 , C07K14/705
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公开(公告)号:EP0946183A4
公开(公告)日:2001-07-18
申请号:EP97946363
申请日:1997-10-29
申请人: MERCK & CO INC
IPC分类号: C07D237/24 , A61K31/00 , A61K31/50 , A61K31/66 , A61K31/664 , A61K45/00 , A61P9/06 , A61P9/00
CPC分类号: A61K31/664 , A61K31/00 , A61K31/50 , A61K31/66 , Y10S514/821
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公开(公告)号:EP1517917A4
公开(公告)日:2005-10-12
申请号:EP01995166
申请日:2001-11-16
申请人: MERCK & CO INC
IPC分类号: G01N33/50 , C07K14/47 , C07K14/705 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12Q1/02 , C12Q1/68 , G01N33/15 , C07K14/435 , C07K16/00 , C12N15/63 , G01N33/53
CPC分类号: C07K14/705
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公开(公告)号:EP1224208A4
公开(公告)日:2003-03-05
申请号:EP00968530
申请日:2000-09-29
申请人: MERCK & CO INC
发明人: SWANSON RICHARD J , LIU YUAN , MCKENNA EDWARD
IPC分类号: G01N33/50 , A61K45/00 , A61P9/00 , A61P25/00 , A61P43/00 , C07K14/705 , C07K16/28 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/04 , C12Q1/02 , G01N33/15 , G01N33/68 , C07K1/00 , C07H21/02 , C07H21/04 , C12N5/00 , C12P1/00 , C12P21/06 , G01N33/53
CPC分类号: G01N33/6872 , C07K14/705
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公开(公告)号:EP0948335A4
公开(公告)日:2001-08-22
申请号:EP97946362
申请日:1997-10-29
申请人: MERCK & CO INC
IPC分类号: C07D237/24 , A61K31/00 , A61K31/50 , A61K31/66 , A61K45/00 , A61P9/00 , A61P9/06 , A61P43/00 , C07F9/53
CPC分类号: C07F9/5333 , A61K31/00 , A61K31/50 , A61K31/66 , C07D237/24 , C07F9/532 , C07F9/5325
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