HUMAN HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CATION CHANNEL HCN1
    3.
    发明公开
    HUMAN HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CATION CHANNEL HCN1 审中-公开
    MENSCHLICHER高分子化合物,DURCH ZYKLISCHES NUKLEOTID GESTEUERTER KATIONENKANAL HCN1

    公开(公告)号:EP1407011A4

    公开(公告)日:2004-07-21

    申请号:EP02720890

    申请日:2002-01-18

    申请人: MERCK & CO INC

    CPC分类号: C07K14/705

    摘要: The present invention is directed to novel human DNA sequences encoding human HCN1 proteins, the protein encoded by the DNA sequences, vectors comprising the DNA sequences, host cells containing the vectors, and methods of identifying inhibitors and activators of cation channels containing the human HCN1 proteins.

    摘要翻译: 本发明涉及编码人HCN1蛋白质的新型人DNA序列,由DNA序列编码的蛋白质,包含DNA序列的载体,含有载体的宿主细胞,以及鉴定含有人HCN1蛋白质的阳离子通道的抑制剂和激活剂的方法 。