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1.发明授权DIPHENYL-1,2,3-THIADIAZOL-3-OXIDES, COMPOSITIONS AND METHODS OF USE 有权二苯基-1,2,3-噻二唑-3-氧化物，组合物及其使用方法
公开(公告)号：EP1181284B1
公开(公告)日：2003-07-16
申请号：EP00926600.8
申请日：2000-05-04
IPC分类号： C07D285/06 , A61K31/433 , A61P29/00
CPC分类号： C07D285/06
摘要： The invention encompasses compounds of Formula (I) as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula (I). The invention also encompasses certain pharmaceutical compositions for treatment of COX-2 mediated diseases comprising compounds of Formula (I).
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公开(公告)号：EP1299372A1
公开(公告)日：2003-04-09
申请号：EP01947085.5
申请日：2001-06-28
IPC分类号： C07D309/38 , A61K31/35
CPC分类号： C07D309/38
摘要： The invention encompasses the novel compounds of Formula (I), which are useful in the treatment of cyclooxygenase-2 mediated diseases. The invention also encompasses certain pharmaceutical compositions comprising compounds of Formula (I) as well as methods of treating yclooxygenase-2 mediated diseases comprising administering to a patient in need of such treatment a non-toxic therapeutically effective amount of a compound of Formula (I).
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3.发明公开DIPHENYL-1,2,3-THIADIAZOL-3-OXIDES, COMPOSITIONS AND METHODS OF USE 有权二苯基-1,2,3-噻二唑-3-氧化物，组合物及其使用方法
公开(公告)号：EP1181284A1
公开(公告)日：2002-02-27
申请号：EP00926600.8
申请日：2000-05-04
IPC分类号： C07D285/06 , A61K31/433 , A61P29/00
CPC分类号： C07D285/06
摘要： The invention encompasses compounds of Formula (I) as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula (I). The invention also encompasses certain pharmaceutical compositions for treatment of COX-2 mediated diseases comprising compounds of Formula (I).
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4.发明公开ARYL SUBSTITUTED 5,5 FUSED AROMATIC NITROGEN COMPOUNDS AS ANTI-INFLAMMATORY AGENTS 失效芳基取代的5,5-连接的芳族硝基化合物用作抗炎活性成分
公开(公告)号：EP0802917A1
公开(公告)日：1997-10-29
申请号：EP96900215.0
申请日：1996-01-10
发明人： GAUTHIER, Jacques, Yves , LAU, Cheuk, K. , LEBLANC, Yves , LI, Chun-Sing , ROY, Patrick , THERIEN, Michel , WANG, Zhaoyin
CPC分类号： C07D487/04 , C07D513/04
摘要： The invention encompasses the novel compound of formula (I) as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of formula (I). The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of formula (I).
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