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公开(公告)号：EP2920172A4
公开(公告)日：2016-05-25
申请号：EP13855780
申请日：2013-11-15
申请人： MERCK SHARP & DOHME
发明人： ACHAB ABDELGHANI ABE , ALTMAN MICHAEL D , DENG YONGQI , KATTAR SOLOMON , KATZ JASON D , METHOT JOEY L , ZHOU HUA , MCGOWAN MEREDETH , CHRISTOPHER MATTHEW P , GARCIA YUDITH , ANTHONY NEVILLE JOHN , FRADERA LLINAS FRANCESC XAVIER , YANG LIPING , MU CHANGWEI , WANG XIAONA , SHI FENG , YE BAIJUN , ZHANG SIXING , ZHAO XIAOLI , ZHANG RONG , FONG KIN CHIU , LENG XIANSHENG
CPC分类号： C07D487/04 , A61K31/52 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D473/34 , C07D519/00 , A61K2300/00
摘要： The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflamation, asthma, COPD and cancer.
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2.发明公开PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA 有权纯化ON ON ER ER ER ER TA TA TA TA TA TA TA
公开(公告)号：EP2920171A4
公开(公告)日：2016-06-22
申请号：EP13855335
申请日：2013-11-15
申请人： MERCK SHARP & DOHME
发明人： ACHAB ABDELGHANI ABE , ALTMAN MICHAEL D , DENG YONGQI , GUZI TIMOTHY , KATTAR SOLOMON , KATZ JASON D , METHOT JOEY L , ZHOU HUA , MCGOWAN MEREDETH , CHRISTOPHER MATTHEW P , GARCIA YUDITH , ANTHONY NEVILLE JOHN , FRADERA LLINAS FRANCESC XAVIER , MU CHANGWEI , ZHANG SIXING , ZHANG RONG , FONG KIN CHIU , LENG XIANSHENG
IPC分类号： C07D473/30 , A61K31/52 , A61K31/522 , A61P11/00 , A61P19/02 , A61P35/00 , A61P37/00 , C07D473/00 , C07D473/06 , C07D473/38 , C07D519/00
CPC分类号： A61K31/52 , A61K31/5377 , A61K45/06 , C07D473/00 , C07D473/06 , C07D473/30 , C07D473/38 , C07D519/00 , A61K2300/00
摘要： The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.
摘要翻译： 本发明提供式I化合物，其为PI3K-δ抑制剂，因此可用于治疗PI3K-δ介导的疾病如炎症，哮喘，COPD和癌症。
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