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公开(公告)号:EP3197900A4
公开(公告)日:2018-03-21
申请号:EP15843683
申请日:2015-09-23
发明人: CAI JIAQIANG , CRESPO ALEJANDRO , DU XIAOXING , DUBOIS BYRON GABRIEL , GUIADEEN DEODIALSINGH , KOTHANDARAMAN SHANKARAN , LIU PING , LIU RONGQIANG , QUAN WEIGUO , SINZ CHRISTOPHER , WANG LIPING
IPC分类号: C07D471/04 , A61K31/497 , A61P7/06 , C07D471/06 , C07D498/04 , C07D498/06 , C07D498/16 , C07D513/04 , C07D513/06
CPC分类号: C07D513/06 , C07D471/04 , C07D471/06 , C07D498/04 , C07D498/06 , C07D498/16 , C07D513/04
摘要: The present invention concerns compounds of formula I or pharmaceutically acceptable salts thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.
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公开(公告)号:EP3197455A4
公开(公告)日:2018-04-04
申请号:EP15845304
申请日:2015-09-23
发明人: CAI JIAQIANG , COLANDREA VINCENT , CRESPO ALEJANDRO , DEBENHAM JOHN , DU XIAOXING , GUIADEEN DEODIALSINGH , LIU PING , LIU RONGQIANG , MADSEN DUGGAN CRISTINA B , MCCOY JOSHUA G , QUAN WEIGUO , SINZ CHRISTOPHER , WANG LIPING
IPC分类号: C07D215/56 , A61K31/436 , A61P7/06 , C07D221/22 , C07D417/06 , C07D471/04 , C07D491/052
CPC分类号: C07D491/052 , C07D215/56 , C07D221/22 , C07D417/06 , C07D471/04
摘要: The present invention concerns a compound of formula I or a pharmaceutically acceptable salt thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.
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公开(公告)号:EP3197452A4
公开(公告)日:2018-02-28
申请号:EP15844485
申请日:2015-09-23
发明人: CAI JIAQIANG , CRESPO ALEJANDRO , DEBENHAM JOHN , DU XIAOXING , LIU PING , LIU RONGQIANG , MADSEN-DUGGAN CRISTINA B , QUAN WEIGUO , SINZ CHRISTOPHER , WANG LIPING
IPC分类号: C07D491/048 , A61K31/4355 , A61P7/06 , C07D495/04
CPC分类号: C07D495/04 , A61P7/06 , C07D491/048
摘要: The present invention concerns compounds of formula I or a pharmaceutically acceptable salt thereof which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.
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公开(公告)号:EP3197451A4
公开(公告)日:2018-02-28
申请号:EP15843799
申请日:2015-09-23
发明人: CAI JIAQIANG , CRESPO ALEJANDRO , DU XIAOXING , DUBOIS BYRON GABRIEL , LIU PING , LIU RONGQIANG , QUAN WEIGUO , SINZ CHRISTOPHER , WANG LIPING
IPC分类号: C07D491/04 , A61K31/4355 , A61P7/06 , A61P9/10
CPC分类号: C07D491/048 , A61P7/06 , A61P9/10
摘要: The present invention concerns compounds of formula I or pharmaceutically acceptable salts thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.
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