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公开(公告)号:EP3087060A4
公开(公告)日:2017-06-14
申请号:EP14873215
申请日:2014-12-17
发明人: SHEN DONG-MING , EGBERTSON MELISSA , BERGER RICHARD , QIAN XIAOXIA , QIAN YIMIN , HARPER BART , YANG MENG , GUO ZACK ZHI QIANG , RADA VANESSA L , WANG DEPING , CERNAK TIMOTHY A , SINZ CHRISTOPHER J , WANG MING , WILSON JONATHAN E , XU SHIMIN
IPC分类号: C07D239/36 , A61K31/513 , A61P25/18 , A61P25/22 , A61P25/28 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14
CPC分类号: C07D239/36 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/06 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D413/04 , C07D417/04 , C07D487/04
摘要: Disclosed are pyrimidine carboxamide compounds of formula (I) which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2), pharmaceutical compositions and uses thereof.
摘要翻译: 公开了可用作治疗剂以治疗与磷酸二酯酶2(PDE2)相关的中枢神经系统病症的式(I)的嘧啶甲酰胺化合物,其药物组合物及其用途。