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公开(公告)号：EP2733147A1
公开(公告)日：2014-05-21
申请号：EP13191413.7
申请日：2009-06-16
发明人： Elliott, Eric L. , Ferdous, Abu J. , Kaufman, Michael J. , Komar, Sonja A. , Mazaik, Debra L. , McCubbin, Quentin J. , Nguyen, Phoung M. , Palaniappan, Vaithianathan , Skwierczynski, Raymond D. , Truong, Nobel T. , Varga, Csanad M. , Zawaneh, Peter N.
CPC分类号： C07F5/04 , A61K31/198 , A61K31/454 , A61K31/69 , C07C233/83 , C07F5/025 , C07K5/06139 , C07K5/06191
摘要： The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
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2.发明授权
公开(公告)号：EP2730581B1
公开(公告)日：2016-04-27
申请号：EP13191414.5
申请日：2009-06-16
发明人： Elliott, Eric L. , Ferdous, Abu J. , Kaufman, Michael J. , Komar, Sonja A. , Mazaik, Debra L. , McCubbin, Quentin J. , Nguyen, Phoung M. , Palaniappan, Vaithianathan , Skwierczynski, Raymond D. , Truong, Nobel T. , Varga, Csanad M. , Zawaneh, Peter N.
IPC分类号： C07F5/02 , C07K5/06 , C07F5/04 , C07K5/078 , A61K38/05 , A61K31/198 , A61K31/454 , A61K31/69 , C07C233/83 , A61P29/00 , A61P35/00
CPC分类号： C07F5/04 , A61K31/198 , A61K31/454 , A61K31/69 , C07C233/83 , C07F5/025 , C07K5/06139 , C07K5/06191
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公开(公告)号：EP2730581A1
公开(公告)日：2014-05-14
申请号：EP13191414.5
申请日：2009-06-16
发明人： Elliott, Eric L. , Ferdous, Abu J. , Kaufman, Michael J. , Komar, Sonja A. , Mazaik, Debra L. , McCubbin, Quentin J. , Nguyen, Phoung M. , Palaniappan, Vaithianathan , Skwierczynski, Raymond D. , Truong, Nobel T. , Varga, Csanad M. , Zawaneh, Peter N.
CPC分类号： C07F5/04 , A61K31/198 , A61K31/454 , A61K31/69 , C07C233/83 , C07F5/025 , C07K5/06139 , C07K5/06191
摘要： The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
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公开(公告)号：EP2730580A1
公开(公告)日：2014-05-14
申请号：EP13191412.9
申请日：2009-06-16
发明人： Elliott, Eric L. , FERDOUS, Abu J. , Kaufman, Michael J. , Komar, Sonja A. , Mazaik, Debra L. , McCubbin, Quentin J. , Nguyen, Phoung M. , Palaniappan, Vaithianathan , Skwierczynski, Raymond D. , Truong, Nobel T. , Varga, Csanad M. , Zawaneh, Peter N.
CPC分类号： C07F5/04 , A61K31/198 , A61K31/454 , A61K31/69 , C07C233/83 , C07F5/025 , C07K5/06139 , C07K5/06191
摘要： The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
摘要翻译： 本发明提供用作蛋白酶体抑制剂的新化合物。 本发明还提供了包含本发明化合物的药物组合物和使用该组合物治疗各种疾病的方法。
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5.发明公开Boronate ester compounds and pharmaceutical compositions thereof 审中-公开其Boronatesterverbindungen和药物组合物
公开(公告)号：EP2730579A1
公开(公告)日：2014-05-14
申请号：EP13191409.5
申请日：2009-06-16
发明人： Elliott, Eric L. , Ferdous, Abu J. , Kaufman, Michael J. , Komar, Sonja A. , Mazaik, Debra L. , McCubbin, Quentin J. , Nguyen, Phoung M. , Palaniappan, Vaithianathan , Skwierczynski, Raymond D. , Truong, Nobel T. , Varga, Csanad M. , Zawaneh, Peter N.
CPC分类号： C07F5/04 , A61K31/198 , A61K31/454 , A61K31/69 , C07C233/83 , C07F5/025 , C07K5/06139 , C07K5/06191
摘要： The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
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