摘要:
The present invention provides an automated system and method for packing chromatography columns. In one embodiment, the system first determines the type of media that is present in the column, and uses this information to generate an automated procedure to pack the specific media type. In a second embodiment, the media type is made known to the system, such as via input from the operator. The system then uses this information, in the same manner as in the first embodiment, to generate an automated procedure to pack the specific media type. Finally, in a third embodiment, parameters such as column height and rate of compression are made known to the system, such as via input from the operator. The system then packs the column in accordance with these supplied parameters.
摘要:
A removable alignment device for a filter cartridge (6) that ensures that a port of the filter cartridge is liquid tightly sealed to the port of a head of a housing even if there is insufficient room beneath the bowl to allow one to physically secure the cartridge port to the head port before securing the head and the bowl together. The alignment device comprises a base formed so as to be removably attached to portion of the filter cartridge (6), said base being of a height sufficient to cause the filter cartridge (6) to seat in a filter housing (2,4) when assembled and/or of a width sufficient to center the filter cartridge (6) within the filter housing (2,4) when assembled.
摘要:
Tangential flow filtration device is provided wherein liners are provided between the filtration element and the top and bottom holders or manifolds. The liners incorporate the flow channels and inlet and outlet ports that were previously present in the manifolds. The liners are made of an inexpensive material and therefore are disposable after a single use, making it more cost effective to dispose of them than to clean the conventional manifolds. In addition, the liners can be pre-sterilized.
摘要:
Redundant filtration system that includes at least one barrier filter as a process filter, the barrier filter having both hydrophilic and hydrophobic paths, allowing both fluid and gas permeability. The need for vents is eliminated, as is an intermediate drain filter. The device also can be dried in series. The filtration system includes a network of conduits and receptacles, the network receiving liquid raw and/or starting material at one end, conducting it through the process stream defined thereby, and producing the desired liquid product at another end. The network is provided with one or more inputs for introducing liquid raw material into the fluid process stream, and one or more output ports for discharging fluid out of the fluid process stream. The network is preferably an essentially closed network, and also, preferably sterile and/or aseptic.
摘要:
The present invention provides an automated system and method for packing chromatography columns. In one embodiment, the system first determines the type of media that is present in the column, and uses this information to generate an automated procedure to pack the specific media type. In a second embodiment, the media type is made known to the system, such as via input from the operator. The system then uses this information, in the same manner as in the first embodiment, to generate an automated procedure to pack the specific media type. Finally, in a third embodiment, parameters such as column height and rate of compression are made known to the system, such as via input from the operator. The system then packs the column in accordance with these supplied parameters.
摘要:
A removable alignment device for a filter cartridge (6) that ensures that a port of the filter cartridge is liquid tightly sealed to the port of a head of a housing even if there is insufficient room beneath the bowl to allow one to physically secure the cartridge port to the head port before securing the head and the bowl together. The alignment device comprises a base formed so as to be removably attached to portion of the filter cartridge (6), said base being of a height sufficient to cause the filter cartridge (6) to seat in a filter housing (2,4) when assembled and/or of a width sufficient to center the filter cartridge (6) within the filter housing (2,4) when assembled.