专利检索 ap:("MITSUBISHI PHARMA CORP") AND inv:"TAKAHASHI TSUYOSHI" 第 1 页

1.

发明公开
VIRUS-FREE PLASMA PROTEIN COMPOSITIONS TREATED WITH POROUS MEMBRANE AND PROCESS FOR PRODUCING THE SAME 审中-公开
标题翻译：通过处理，多孔膜，无病毒的血浆蛋白相关的生产过程的装置

公开(公告)号：EP1250929A4

公开(公告)日：2004-12-29

申请号：EP00987665

申请日：2000-12-20

申请人： MITSUBISHI PHARMA CORP

发明人： TAKAHASHI TSUYOSHI , FURUSHIMA KOJI , MORITA MASANORI , TSUJIKAWA MUNEO , URAYAMA TAKERU , HAMATO NOBUAKI

IPC分类号： A61K35/00 , A61L2/00 , A61L2/02 , A61K35/16 , A61K38/36 , A61K38/37 , A61K38/39 , C07K14/75 , C07K14/755 , C07K14/78

CPC分类号： A61L2/0017 , A61K35/00

摘要： Contaminant viruses can be efficiently removed almost without losing the activity of protein by subjecting a plasma protein composition having a high risk of viral contamination to a treatment with a porous membrane having a pore size greater than a single-particle size of the virus, particularly by subjecting a plasma protein composition to a fractionation treatment by precipitation, before the porous membrane treatment. Particularly, a fibrinogen composition substantially free of non-enveloped viruses, Parvovirus among others, can be provided. By the application of the present invention, a safe plasma protein preparation free of viruses can be conveniently provided.