专利检索 ap:("Massachusetts Institute of Technology" OR "The Brigham AND Women's Hospital, Inc.") AND inv:"CHO, Woo, Kyung" 第 1 页

1.

发明授权
ADHESIVE ARTICLES CONTAINING A COMBINATION OF SURFACE MICROPATTERNING AND REACTIVE CHEMISTRY AND METHODS OF MAKING AND USING THEREOF 有权

公开(公告)号：EP2925376B1

公开(公告)日：2019-07-17

申请号：EP13808373.8

申请日：2013-11-27

申请人： Massachusetts Institute of Technology , The Brigham and Women's Hospital, Inc.

发明人： PEREIRA, Maria, Jose M.N. , CHO, Woo, Kyung , LANGER, Robert, S. , KARP, Jeffrey, M.

IPC分类号： A61L15/14 , A61L15/58 , A61L24/00 , A61L24/06

2.

发明公开
ADHESIVE ARTICLES CONTAINING A COMBINATION OF SURFACE MICROPATTERNING AND REACTIVE CHEMISTRY AND METHODS OF MAKING AND USING THEREOF 审中-公开
标题翻译：进行生产及其用途表面微结构与活性化学和方法的组合粘合剂制品

公开(公告)号：EP2925376A1

公开(公告)日：2015-10-07

申请号：EP13808373.8

申请日：2013-11-27

申请人： Massachusetts Institute of Technology , The Brigham and Women's Hospital, Inc.

发明人： PEREIRA, Maria, Jose M.N. , CHO, Woo, Kyung , LANGER, Robert, S. , KARP, Jeffrey, M.

IPC分类号： A61L15/14 , A61L15/58 , A61L24/00 , A61L24/06

CPC分类号： A61B17/11 , A61L15/26 , A61L15/42 , A61L15/44 , A61L15/58 , A61L15/62 , A61L15/64 , C08L67/04

摘要： Adhesive articles containing microtopography, such as microprotrusions, and a coating of adhesive glue, such an adhesive having known toxicity and/or tissue reactive functional groups are described herein. The articles described herein contain a substrate, a plurality of microfeatures, and an adhesive, such as an adhesive glue. The articles described herein exhibit a 90° pull off adhesion of at least about 1.5 N/cm2. The articles described herein can contain less adhesive than when the adhesive is used alone without microtopography and yet exhibit equivalent adhesive strength with little or no toxicity or other adverse side effects (e.g., exothermic reaction).

3.

发明公开
DEPLOYABLE BARBED MICRONEEDLE ARRAY AND USES THEREOF 审中-公开
标题翻译： WITH MICRO NEEDLES部署阵列倒钩及其用途

公开(公告)号：EP2665504A1

公开(公告)日：2013-11-27

申请号：EP12736202.8

申请日：2012-01-18

申请人： Massachusetts Institute Of Technology , The Brigham and Women's Hospital, Inc.

发明人： KARP, Jeffrey, M. , CHO, Woo, Kyung , LAULICHT, Bryan , ANKRUM, James, A. , KARNIK, Rohit, N. , LANGER, Robert

IPC分类号： A61M5/32

CPC分类号： A61B17/205 , A61M37/0015 , A61M2037/0046 , A61M2037/0053 , A61M2037/0061

摘要： The present disclosure provides devices and uses thereof. A devices disclosed herein comprises one or more tips, wherein the one or more tips are designed and constructed to initiate penetration by the device; and one or more protrusions in a region adjacent to each tip. In some embodiments, one or more protrusions can be constructed and arranged so that the required penetration force is reduced as compared with that observed for an otherwise identical device lacking the one or more protrusions. Additionally or alternatively, one or more protrusions can be constructed and arranged such that the required pull-out force is increased as compared with that observed for an otherwise identical device lacking the one or more protrusions.