专利检索 ap:("Matsuo, Masafumi" OR "Nonprofit Organization Translational Research Organization of Duchenne Muscular Dystrophy" OR "Takeshima, Yasuhiro") AND inv:"KOIZUMI, Makoto, c/o Sankyo Company, Ltd." 第 1 页

1.

发明公开
ENA NUCLEIC ACID DRUGS MODIFYING SPLICING IN mRNA PRECURSOR 审中-公开
标题翻译： ENA-NUKLEINSÄUREARZNEIMITTEL，DIE DAS SPLICING IM mRNA-VORLÄUFERVERÄNDERN

公开(公告)号：EP1568769A1

公开(公告)日：2005-08-31

申请号：EP03774151.9

申请日：2003-11-21

申请人： Matsuo, Masafumi , Nonprofit Organization Translational Research Organization of Duchenne Muscular Dystrophy , Takeshima, Yasuhiro

发明人： MATSUO, Masafumi, Kobe Univ.Graduate Sch.Medicine , TAKESHIMA, Yasuhiro, c/o Kobe Univ.Grad.Sch.Med. , KOIZUMI, Makoto, c/o Sankyo Company, Ltd.

IPC分类号： C12N15/11 , C07H21/04 , A61K31/7088 , A61K31/712 , A61K31/7125 , A61K48/00 , A61P21/04

CPC分类号： C07H21/04 , A61K38/00 , A61K48/00 , C12N15/113 , C12N2310/11 , C12N2310/3231 , C12N2320/33

摘要： Oligonucleotides having a nucleotide sequence complementary to nucleotide numbers such as 2571-2607, 2578-2592, 2571-2592, 2573-2592, 2578-2596, 2578-2601 or 2575-2592 of the dystrophin cDNA (Gene Bank accession No. NM_004006.1) and therapeutic agents for muscular dystrophy comprising such oligonucleotides.

摘要翻译： 具有与核苷酸序列互补的核苷酸序列的寡核苷酸，例如抗肌萎缩蛋白cDNA（Gene Bank登录号NM_004006）的2571-2607,2578-2592,2571-2592,2573-2592,2578-2596,2578-2601或2575-2592。 1）和包含这种寡核苷酸的肌营养不良的治疗剂。