公开(公告)号：EP1817620A2

公开(公告)日：2007-08-15

申请号：EP05812037.9

申请日：2005-10-21

申请人： Mauna Kea Technologies

发明人： VIELLEROBE, Bertrand ,  LACOMBE, Francois ,  LOISEAU, Alexandre ,  LOURADOUR, Frédéric ,  LELEK, Michael ,  BARTHELEMY, Alain

IPC分类号： G02B21/00 ,  G02B21/16

CPC分类号： G02B23/2484 ,  A61B5/0062 ,  A61B5/0068 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0086 ,  G01N21/6452 ,  G01N21/6458 ,  G01N2021/6417 ,  G01N2021/6484 ,  G01N2201/08 ,  G01N2201/1053 ,  G02B6/04 ,  G02B21/002 ,  G02B21/16 ,  G02B23/2469

摘要： The invention relates to a system for carrying out fibered multiphoton microscopic imagery of a sample (10) for use in endoscopy or fluorescence microscopy. This system comprises: a femtosecond pulsed laser (1, 2) for generating a multiphoton excitation laser radiation; an image guide (8) comprised of a number of optical fibers and permitting the sample to be illuminated by a point-by-point scanning in a subsurface plane; pre-compensating means (4) for pre-compensating for dispersion effects of the excitation pulses in the image guide (8), these means being situated between the pulsed laser and the image guide (8); scanning means for directing, in succession, the excitation laser beam in a fiber of the image guide, and; in particular, an optical head (9) for focussing the excitation laser beam exiting the image guide in the sample (10).