公开(公告)号：EP4328577A2

公开(公告)日：2024-02-28

申请号：EP23220833.0

申请日：2019-08-20

申请人： Mayo Foundation for Medical Education and Research ,  Industry-University Cooperation Foundation Hanyang University

发明人： JANG, Dong-Pyo ,  LEE, Kendall H. ,  OH, Yoonbae ,  KIMBLE, Christopher J.

IPC分类号： G01N27/327

摘要： Systems, methods, and devices for generating multiple cyclic square-waveforms and sloped-edge square waveforms. Aspects of the techniques disclosed herein include applying the generated waveforms to an electrode used in voltammetry, e.g., to measure a level of a neurochemical in neural tissue. An electrode can be located in a solution, and an electrical stimulus applied to the solution through the electrode using a multiple cyclic square waveform. An electrical current response to the stimulus is measured, and a level of an analyte (e.g., dopamine or other neurochemical(s)) determined based on the electrical current response.

公开(公告)号：EP4328577A3

公开(公告)日：2024-06-05

申请号：EP23220833.0

申请日：2019-08-20

申请人： Mayo Foundation for Medical Education and Research ,  Industry-University Cooperation Foundation Hanyang University

发明人： JANG, Dong-Pyo ,  LEE, Kendall H. ,  OH, Yoonbae ,  KIMBLE, Christopher J.

IPC分类号： A61B5/145 ,  G01N27/327

CPC分类号： G01N27/3277 ,  A61B5/14528 ,  A61B5/14546 ,  H03K5/153 ,  H03K4/023 ,  H03K4/063

摘要： Systems, methods, and devices for generating multiple cyclic square-waveforms and sloped-edge square waveforms. Aspects of the techniques disclosed herein include applying the generated waveforms to an electrode used in voltammetry, e.g., to measure a level of a neurochemical in neural tissue. An electrode can be located in a solution, and an electrical stimulus applied to the solution through the electrode using a multiple cyclic square waveform. An electrical current response to the stimulus is measured, and a level of an analyte (e.g., dopamine or other neurochemical(s)) determined based on the electrical current response.