公开(公告)号：EP2217225A2

公开(公告)日：2010-08-18

申请号：EP08837381.6

申请日：2008-10-07

申请人： Mazence Inc. ,  KT & G Co., Ltd.

发明人： JO, In Geun ,  YOO, Sang-Ku ,  PARK, Myung-Gyu ,  KWAK, Taehwan

IPC分类号： A61K31/122 ,  A61K31/352 ,  A61K31/34

CPC分类号： A61K31/122 ,  A61K9/14 ,  A61K9/143 ,  A61K9/145 ,  A61K9/5026 ,  A61K9/5042

摘要： Provided is a pharmaceutical composition having excellent in vivo absorption properties by increasing solubility and absorption rate of a sparingly-soluble naphthoquinone-based compound via incorporation of micronized particles of a certain naphthoquinone-based compound.

公开(公告)号：EP2231148A2

公开(公告)日：2010-09-29

申请号：EP08868312.3

申请日：2008-12-18

申请人： Mazence Inc. ,  KT & G Corporation

发明人： KWAK, Taehwan ,  PARK, Myung-Gyu

IPC分类号： A61K31/352

CPC分类号： C07D405/12 ,  A61K31/352 ,  C07D307/92 ,  C07D311/78 ,  C07D311/92 ,  C07D311/96 ,  C07D327/06 ,  C07D333/74 ,  C07D335/08

摘要： Provided is a pharmaceutical composition for the treatment and prevention of cardiac diseases, containing (a) a therapeutically effective amount of a compound represented by Formula 1 or 2 or a pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, and (b) a pharmaceutically acceptable carrier, diluent or excipient or any combination thereof.

公开(公告)号：EP2520294A2

公开(公告)日：2012-11-07

申请号：EP10841215.6

申请日：2010-12-27

申请人： Mazence Inc.

发明人： KWAK, Tae Hwan ,  PARK, Myung-Gyu ,  SO, Hong-Seob ,  PARK, Raekil ,  KIM, Hyung-Jin

IPC分类号： A61K31/352 ,  A61P27/16

CPC分类号： A61K31/352 ,  A61K31/343 ,  A61K31/381 ,  A61K31/382 ,  A61K31/39

摘要： The present invention relates to a composition for treating or preventing hearing loss comprising naphthoquinone-based compounds.

摘要翻译： 本发明涉及一种组合物，用于治疗或预防听力损失包括基于萘醌系化合物等。

公开(公告)号：EP2231146A2

公开(公告)日：2010-09-29

申请号：EP08864328.3

申请日：2008-12-18

申请人： Mazence Inc. ,  KT & G Corporation

发明人： PARK, Myung-Gyu ,  KWAK, Taehwan

IPC分类号： A61K31/35

CPC分类号： A61K31/343 ,  A61K31/352

摘要： Provided is a pharmaceutical composition for the treatment and prevention of glaucoma, containing (a) a therapeutically effective amount of a compound represented by Formula 1 or a pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, and (b) a pharmaceutically acceptable carrier, diluent or excipient or any combination thereof.

公开(公告)号：EP2222295A2

公开(公告)日：2010-09-01

申请号：EP08866609.4

申请日：2008-12-18

申请人： Mazence Inc. ,  KT & G Corporation

发明人： KWAK, Taehwan ,  PARK, Myung-Gyu ,  JUNG, Kyoung Hoon

IPC分类号： A61K31/352

CPC分类号： C07D311/92 ,  A61K31/352 ,  C07D307/77 ,  C07D307/92 ,  C07D311/78 ,  C07D311/96 ,  C07D327/06 ,  C07D333/74 ,  C07D335/08 ,  C07D405/12 ,  Y10T428/2982

摘要： Provided is a pharmaceutical composition for the treatment and prevention of kidney diseases, containing (a) a therapeutically effective amount of a compound represented by Formulae 1 or 2 or a pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, and (b) a pharmaceutically acceptable carrier, diluent or excipient or any combination thereof.