专利检索 ap:("MediGene Aktiengesellschaft") AND inv:"BERTRAN, Joan" 第 1 页

1.

发明公开
WIRTSZELLEN ZUR VERPACKUNG VON REKOMBINANTEM ADENO-ASSOZIIERTEM VIRUS (RAAV), VERFAHREN ZU IHRER HERSTELLUNG UND DEREN VERWENDUNG 审中-公开
标题翻译：宿主细胞的重组腺相关病毒（腺相关病毒）方法的包装用于生产和它们的用途

公开(公告)号：EP1315798A2

公开(公告)日：2003-06-04

申请号：EP01967320.1

申请日：2001-09-07

申请人： MediGene Aktiengesellschaft

发明人： BERTRAN, Joan , MOEBIUS, Ulrich , HÖRER, Markus , REHBERGER, Bernd

IPC分类号： C12N5/10 , C12N15/86

CPC分类号： C12N7/00 , A61K48/00 , C07K14/005 , C12N15/86 , C12N2750/14122 , C12N2750/14143 , C12N2750/14152

摘要： The invention relates to host cells for packing a recombinant adeno-associated virus (rAAV). Said cells contain at least one copy of a first auxiliary construct for expressing at least one AAV Rep protein, and at least one copy of another auxiliary construct for expressing at least one AAV Cap protein. The invention also relates to auxiliary constructs for expressing at least one AAV Rep protein and one AAV Cap protein in a host cell; vector constructs comprising at least one nucleic acid which is heterologous in relation to the AAV; a method for producing a host cell for packing a recombinant adeno-associated virus (rAAV); and the use of the host cell for producing an rAAV.