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公开(公告)号：EP3804736A1
公开(公告)日：2021-04-14
申请号：EP19815851.1
申请日：2019-06-05
申请人： Medipost Co., Ltd.
发明人： YANG, Yun Sun , OH, Wonil , CHOI, Soo Jin , KWAK, Jihye , KIM, Dong Hyon , LIM, Hoon
摘要： The present invention relates to a pharmaceutical composition comprising HLA-A2-expressing mesenchymal stem cells as an effective ingredient for prevention or treatment of inflammatory disease. According to the present invention, the mesenchymal stem cells expressing HLA-A2 on the surface thereof inhibit the secretion of the inflammatory cytokine TNF-a and increase the expression of the anti-inflammatory markers CD163 and Arg-1, so that the pharmaceutical composition comprising the mesenchymal stem cells as an effective ingredient can be advantageously used for suppressing inflammation or treating inflammatory diseases.
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2.发明公开HAIR GROWTH-PROMOTING FUNCTION OF SMALL-SIZED STEM CELLS AND USE THEREOF 审中-公开侠盗猎车手VON KLEINEN STAMMZELLEN UND VERWENDUNG DAVON
公开(公告)号：EP3146973A1
公开(公告)日：2017-03-29
申请号：EP15819530.5
申请日：2015-03-02
申请人： Medipost Co., Ltd.
发明人： YANG, Yoon Sun , OH, Wonil , LEE, Jang Young , CHOI, Soo Jin , JEON, Hong Bae , KIM, Ju-Yeon , LIM, Hoon
CPC分类号： A61K8/981 , A61K8/982 , A61K8/983 , A61K35/28 , A61K35/51 , A61K2800/412 , A61K2800/91 , A61Q7/00 , C12N5/0665 , C12N2502/092
摘要： Provided are a composition for preventing hair loss and stimulating hair growth, which includes small-sized stem cells, particularly, small-sized stem cells having a diameter of 8 µm or less, or a conditioned medium thereof as an active ingredient, a method of preparing the same, and a use of the same. Provided is a use of the composition utilizing a hair growth stimulating function of the small-sized stem cells having a diameter of 8 µm or less to considerably increase activity of hair follicle stem cells in a telogen phase.
摘要翻译： 提供一种防止脱发和刺激毛发生长的组合物，其包括小型干细胞，特别是直径为8μm以下的小型干细胞或其条件培养基作为活性成分，其方法为 准备相同，并使用相同的。 提供了利用直径为8μm以下的小型干细胞的毛发生长刺激功能的组合物的使用，以显着增加前期阶段的毛囊干细胞的活性。
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公开(公告)号：EP3146973B1
公开(公告)日：2020-05-06
申请号：EP15819530.5
申请日：2015-03-02
申请人： Medipost Co., Ltd.
发明人： YANG, Yoon Sun , OH, Wonil , LEE, Jang Young , CHOI, Soo Jin , JEON, Hong Bae , KIM, Ju-Yeon , LIM, Hoon
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