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公开(公告)号：EP2091426A2
公开(公告)日：2009-08-26
申请号：EP07871618.0
申请日：2007-11-28
申请人： MEDTRONIC, INC.
CPC分类号： A61B5/076 , A61B5/0031 , A61B5/1107 , A61B5/686 , A61B90/39 , A61B2017/00411 , A61B2090/3908 , A61B2090/397 , A61B2090/3975 , A61B2562/0209 , A61B2562/046
摘要： Medical systems and methods incorporate monitoring of at least two implanted markers, each of which is adapted to wirelessly transmit a signal in response to a wirelessly transmitted excitation signal; the response signals are converted into positional information for the two markers. The systems and methods further incorporate both, or one of, an implanted sensing member and/or an implanted therapy delivery device. Signals received from the sensing member may be collated with the positional information. A therapy delivered from the therapy delivery device may be adjusted according to the positional information.
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公开(公告)号：EP2091426B1
公开(公告)日：2015-10-28
申请号：EP07871618.0
申请日：2007-11-28
申请人： Medtronic, Inc.
CPC分类号： A61B5/076 , A61B5/0031 , A61B5/1107 , A61B5/686 , A61B90/39 , A61B2017/00411 , A61B2090/3908 , A61B2090/397 , A61B2090/3975 , A61B2562/0209 , A61B2562/046
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3.发明公开REAL-TIME OPTIMIZATION OF RIGHT TO LEFT VENTRICULAR TIMING SEQUENCE IN BI-VENTIRCULAR PACING OF HEART FAILURE PATIENTS 有权在双心室起搏心力衰竭患者左/右心室时间序列的实时优化
公开(公告)号：EP1735049A1
公开(公告)日：2006-12-27
申请号：EP05725022.7
申请日：2005-03-07
申请人： MEDTRONIC, INC.
CPC分类号： A61N1/368 , A61N1/3627 , A61N1/36521 , A61N1/3684
摘要： A system and automated method for assessing ventricular synchrony in ambulatory patients is provided including at least one mechanical sensor (e.g., accelerometer, tensiometric sensor, force transducer, and the like) operatively coupled to a first myocardial location in order to measure a wall motion signal of a first chamber, and a second mechanical sensor operatively coupled to a second myocardial location in order to measure a wall motion signal of a second chamber. The wall motion signals are processed in order to identify the time at which a fiducial (e.g., an inflection point, a threshold crossing, a maximum amplitude, etc.) occurs for each respective signal. The temporal separation between the fiducial points on each respective signal is measured as a metric of ventricular synchrony and can be optionally utilized to adjust pacing therapy timing to improve synchrony.
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4.发明公开SYSTEMS AND METHODS FOR MONITORING EFFECTIVENESS OF CONGESTIVE HEART FAILURE THERAPY 审中-公开系统和方法监测治疗有效性充血性心脏衰竭
公开(公告)号：EP2124733A2
公开(公告)日：2009-12-02
申请号：EP08728240.6
申请日：2008-01-25
申请人： Medtronic, Inc.
发明人： SOWELAM, Sameh , MARKOWITZ, H. Toby
IPC分类号： A61B5/042 , A61B5/0285
CPC分类号： A61B5/6826 , A61B5/0285 , A61B5/042 , A61B5/053 , A61B5/08 , A61B5/14551 , A61B5/4818 , A61B5/6838
摘要： A method for monitoring a patient includes measuring a series of consecutive pulse transit times (PTT's) of the patient, and processing the resulting PTT signal to detect a presence or absence of central sleep apnea (CSA). The method further includes determining an effectiveness of congestive heart failure therapy, which is being provided to the patient, based on the detected presence or absence of CSA. A system incorporating the method includes an electrode of an implantable medical device, which is adapted to pick up the patient's ventricular depolarization signals, a sensor, which is adapted to pick up peripheral arterial pulse signals of the patient, and a signal processor, which is adapted to receive the two types of signals and to process the signals according to the method. The system may provide the therapy via cardiac resynchronization pacing and, upon detection of CSA, the system may adjust at least one pacing parameter.
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5.发明授权REAL-TIME OPTIMIZATION OF RIGHT TO LEFT VENTRICULAR TIMING SEQUENCE IN BI-VENTIRCULAR PACING OF HEART FAILURE PATIENTS 有权在双心室起搏心力衰竭患者左/右心室时间序列的实时优化
公开(公告)号：EP1735049B1
公开(公告)日：2009-09-02
申请号：EP05725022.7
申请日：2005-03-07
申请人： MEDTRONIC, INC.
CPC分类号： A61N1/368 , A61N1/3627 , A61N1/36521 , A61N1/3684
摘要： A system and automated method for assessing ventricular synchrony in ambulatory patients is provided including at least one mechanical sensor (e.g., accelerometer, tensiometric sensor, force transducer, and the like) operatively coupled to a first myocardial location in order to measure a wall motion signal of a first chamber, and a second mechanical sensor operatively coupled to a second myocardial location in order to measure a wall motion signal of a second chamber. The wall motion signals are processed in order to identify the time at which a fiducial (e.g., an inflection point, a threshold crossing, a maximum amplitude, etc.) occurs for each respective signal. The temporal separation between the fiducial points on each respective signal is measured as a metric of ventricular synchrony and can be optionally utilized to adjust pacing therapy timing to improve synchrony.
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