公开(公告)号：EP1683805A1

公开(公告)日：2006-07-26

申请号：EP04792603.5

申请日：2004-10-19

申请人： Meiji Seika Kaisha, Ltd.

发明人： YOSHIKAWA, Masayuki, Kyoto Pharmaceutical Uni. ,  MATSUDA, Hisashi, Kyoto Pharmaceutical Uni. ,  YAMAGISHI, Megumi, Meiji Seika Kaisha, Ltd. ,  MATSUMOTO, Hitoshi, Meiji Seika Kaisha, Ltd.

IPC分类号： C07H17/065 ,  A61K31/7048 ,  A61K36/18 ,  A23L1/30 ,  C12N9/99 ,  A61P3/10 ,  A61P9/10 ,  A61P13/00 ,  A61P25/00 ,  A61P27/02 ,  A61P43/00

CPC分类号： A61K31/7048 ,  A23L2/52 ,  A23L33/105 ,  A23V2002/00 ,  A61K36/185 ,  A23V2250/2104

摘要： Provided are: an inhibitor of the formation of an advanced glycation end product (AGE) and aldose reductase for treating and preventing both various diseases relating to AGE formation, such as complications related to diabetes and various diseases relating to aldose reductase inhibition; pharmaceutical preparations, compositions, and food and drink that contain these active ingredients; and pharmaceutical preparations and foods prepared by blending compositions containing anthocyanin, because such anthocyanin obtained through condensation or extraction from raw plant materials or the like is useful as an inhibitor of AGE formation and aldose reductase.

摘要翻译： 提供：形成晚期糖基化终产物（AGE）和醛糖还原酶的抑制剂，用于治疗和预防与AGE形成有关的各种疾病，例如与糖尿病有关的并发症和与醛糖还原酶抑制有关的各种疾病; 药物制剂，组合物和含有这些活性成分的食物和饮料; 以及通过配合含有花色素苷的组合物配制的药物制剂和食品，因为通过从原料等冷凝或提取得到的花青素可用作AGE形成抑制剂和醛糖还原酶。