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1.发明授权1 H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZIOSOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF 有权1H吲唑，苯并噻唑，1,2-苯并异恶唑，1,2-苯并异噻唑及其制备和用途和色酮
公开(公告)号：EP1745046B1
公开(公告)日：2011-04-13
申请号：EP05747486.8
申请日：2005-05-06
发明人： XIE, Wenge , HERBERT, Brian , SCHUMACHER, Richard A. , MA, Jianguo , NGUYEN, Truc, Minh , GAUSS, Carla, Maria , TEHIM, Ashok
IPC分类号： C07D471/08 , C07D487/08 , A61K31/4985 , A61K31/551 , A61P25/28
CPC分类号： C07D471/08 , C07D487/08
摘要： The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
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2.发明公开1 H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZOISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF 审中-公开1H吲唑，苯并噻唑，1,2-苯并异恶唑，1,2-苯并异噻唑与色酮类及其制备和应用
公开(公告)号：EP1963332A1
公开(公告)日：2008-09-03
申请号：EP06837344.8
申请日：2006-11-09
发明人： SCHUMACHER, Richard A. , MA, Jianguo , HERBERT, Brian , DANCA, Mihaela Diana , XIE, Wenge , NGUYEN, Truc Minh , TEHIM, Ashok
IPC分类号： C07D487/08 , A61K31/551 , A61P25/28
CPC分类号： C07D471/08 , C07D487/08
摘要： The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of -disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
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3.发明公开1 H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZIOSOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF 有权1H吲唑，苯并噻唑，1,2-苯并异恶唑，1,2-苯并异噻唑及其制备和用途和色酮
公开(公告)号：EP1745046A2
公开(公告)日：2007-01-24
申请号：EP05747486.8
申请日：2005-05-06
发明人： XIE, Wenge , HERBERT, Brian , SCHUMACHER, Richard A. , MA, Jianguo , NGUYEN, Truc, Minh , GAUSS, Carla, Maria , TEHIM, Ashok
IPC分类号： C07D471/08 , C07D487/08 , A61K31/4985 , A61K31/551 , A61P25/28
CPC分类号： C07D471/08 , C07D487/08
摘要： The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
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