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公开(公告)号：EP1044000B1
公开(公告)日：2002-06-12
申请号：EP98959424.7
申请日：1998-11-12
申请人： MERCK & CO., INC.
发明人： VACCA, Joseph, P. , LIN, Jiunn, H. , YEH, Kuang, C. , CHODAKEWITZ, Jeffrey, A. , DEUTSCH, Paul, J. , JU, William, D.
IPC分类号： A61K31/495
CPC分类号： A61K31/7072 , A61K31/495 , A61K31/52 , A61K31/535 , A61K31/70 , A61K38/06 , A61K45/06 , A61K31/445 , A61K2300/00
摘要： The combination of the HIV protease inhibitor Compound A and one or more nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, or protease inhibitors is useful in the inhibition of HIV protease, the inhibition of HIV reverse transcriptase, the prevention or treatment of AIDS, either as compounds, pharmaceutically acceptable salts or esters, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
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公开(公告)号：EP0774969A1
公开(公告)日：1997-05-28
申请号：EP95930118.0
申请日：1995-08-07
申请人： Merck & Co., Inc.
CPC分类号： A61K31/496 , A61K31/4709 , A61K31/435 , A61K31/427 , A61K2300/00
摘要： The combination of the HIV protease inhibitor Compound J and any one or more of four other potent HIV protease inhibitors is useful in the inhibition of HIV protease, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
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公开(公告)号：EP0774969B8
公开(公告)日：2003-07-02
申请号：EP95930118.5
申请日：1995-08-07
申请人： Merck & Co., Inc.
IPC分类号： A61K31/495 , A61K31/435 , A61K31/425
CPC分类号： A61K31/496 , A61K31/4709 , A61K31/435 , A61K31/427 , A61K2300/00
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公开(公告)号：EP0774969B1
公开(公告)日：2003-02-19
申请号：EP95930118.5
申请日：1995-08-07
申请人： Merck & Co., Inc.
IPC分类号： A61K31/495 , A61K31/435 , A61K31/425
CPC分类号： A61K31/496 , A61K31/4709 , A61K31/435 , A61K31/427 , A61K2300/00
摘要： The combination of the HIV protease inhibitor Compound J and any one or more of four other potent HIV protease inhibitors is useful in the inhibition of HIV protease, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
摘要翻译： HIV蛋白酶抑制剂化合物J与四种其他强效HIV蛋白酶抑制剂中的任何一种或多种的组合可用于抑制HIV蛋白酶，预防或治疗HIV感染和治疗AIDS，作为化合物，药学上可接受的 盐，药物组合物成分，不论是否与其他抗病毒剂组合，免疫调节剂，抗生素或疫苗。 还描述了治疗AIDS的方法和预防或治疗HIV感染的方法。
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公开(公告)号：EP1044000A1
公开(公告)日：2000-10-18
申请号：EP98959424.7
申请日：1998-11-12
申请人： MERCK & CO., INC.
发明人： VACCA, Joseph, P. , LIN, Jiunn, H. , YEH, Kuang, C. , CHODAKEWITZ, Jeffrey, A. , DEUTSCH, Paul, J. , JU, William, D.
IPC分类号： A61K31/495
CPC分类号： A61K31/7072 , A61K31/495 , A61K31/52 , A61K31/535 , A61K31/70 , A61K38/06 , A61K45/06 , A61K31/445 , A61K2300/00
摘要： The combination of the HIV protease inhibitor Compound A and one or more nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, or protease inhibitors is useful in the inhibition of HIV protease, the inhibition of HIV reverse transcriptase, the prevention or treatment of AIDS, either as compounds, pharmaceutically acceptable salts or esters, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
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