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    ADAMTS BINDING IMMUNOGLOBULINS
    3.
    发明公开
    ADAMTS BINDING IMMUNOGLOBULINS 审中-实审

    公开(公告)号：EP4272822A3

    公开(公告)日：2024-03-27

    申请号：EP23184254.3

    申请日：2018-06-04

    申请人： Merck Patent GmbH ,  Ablynx N.V.

    发明人： BUYSE, Marie-Ange ,  HERMANS, Guy ,  LINDEMANN, Sven ,  GUEHRING, Hans ,  GUENTHER, Ralf ,  KELLNER, Roland

    IPC分类号： C07K16/40 ,  A61K39/395 ,  A61P19/02

    摘要： The present invention relates to immunoglobulins that bind ADAMTSS and more in particular to polypeptides, that comprise or essentially consist of one or more such immunoglobulins (also referred to herein as "immunoglobulin(s) of the invention", and "polypeptides of the invention", respectively). The invention also relates to constructs comprising such immunoglobulins, such as immunoglobulin single variable domains (ISVDs) or polypeptides as well as nucleic acids encoding such immunoglobulins or polypeptides (also referred to herein as "nucleic acid(s) of the invention"; to methods for preparing such immunoglobulins, polypeptides and constructs; to host cells expressing or capable of expressing such immunoglobulins or polypeptides; to compositions, and in particular to pharmaceutical compositions, that comprise such immunoglobulins, polypeptides, constructs, nucleic acids and/or host cells; and to uses of immunoglobulins, polypeptides, constructs, nucleic acids, host cells and/or compositions, in particular for prophylactic and/or therapeutic purposes, such as the prophylactic and/or therapeutic purposes mentioned herein. Other aspects, embodiments, advantages and applications of the invention will become clear from the further description herein.

    ADAMTS BINDING IMMUNOGLOBULINS
    4.
    发明公开
    ADAMTS BINDING IMMUNOGLOBULINS 审中-公开

    公开(公告)号：EP4272822A2

    公开(公告)日：2023-11-08

    申请号：EP23184254.3

    申请日：2018-06-04

    申请人： Merck Patent GmbH ,  Ablynx N.V.

    发明人： BUYSE, Marie-Ange ,  HERMANS, Guy ,  LINDEMANN, Sven ,  GUEHRING, Hans ,  GUENTHER, Ralf ,  KELLNER, Roland

    IPC分类号： A61P19/02

    摘要： The present invention relates to immunoglobulins that bind ADAMTSS and more in particular to polypeptides, that comprise or essentially consist of one or more such immunoglobulins (also referred to herein as "immunoglobulin(s) of the invention", and "polypeptides of the invention", respectively). The invention also relates to constructs comprising such immunoglobulins, such as immunoglobulin single variable domains (ISVDs) or polypeptides as well as nucleic acids encoding such immunoglobulins or polypeptides (also referred to herein as "nucleic acid(s) of the invention"; to methods for preparing such immunoglobulins, polypeptides and constructs; to host cells expressing or capable of expressing such immunoglobulins or polypeptides; to compositions, and in particular to pharmaceutical compositions, that comprise such immunoglobulins, polypeptides, constructs, nucleic acids and/or host cells; and to uses of immunoglobulins, polypeptides, constructs, nucleic acids, host cells and/or compositions, in particular for prophylactic and/or therapeutic purposes, such as the prophylactic and/or therapeutic purposes mentioned herein. Other aspects, embodiments, advantages and applications of the invention will become clear from the further description herein.